Department of Environmental Health Engineering, Food Safety Division, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
Department of Environmental Health Engineering, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
Rev Environ Health. 2023 Apr 13;39(3):531-537. doi: 10.1515/reveh-2022-0263. Print 2024 Sep 25.
Exposure of infants to chemicals during their development will have major effects on their health. One of the major exposures of infants to chemicals is through their food. The main structure of infant food is milk, which is high in fat. There is a possibility of accumulation of environmental pollution, including benzo () pyrene (BaP). In this systematic review, the amount of BaP in infant milk was surveyed for this purpose. The chosen keywords were: benzo () pyrene, BaP, Infant formula, dried milk, powdered milk, and baby food. A total of 46 manuscripts were found in the scientific database. After initial screening and quality assessment, 12 articles were selected for extraction of data. By meta-analysis, the total estimate of BaP in baby food was calculated to be 0.078 ± 0.006 μg/kg. Estimation of daily intake (EDI) and Hazard Quotient (HQ) for noncarcinogenic risk and Margin of exposure (MOE) for carcinogenic risk were also calculated for three age groups 0-6 months, 6-12 months, and 1-3 years. HQ was lower than 1 and MOE was more than 10,000 for three age groups. Therefore, there is no potential carcinogenic and non-carcinogenic risk for infant health.
婴儿在发育过程中接触化学物质会对其健康产生重大影响。婴儿接触化学物质的主要途径之一是通过他们的食物。婴儿食品的主要结构是高脂肪的牛奶。有可能会积累包括苯并（）芘（BaP）在内的环境污染。在这项系统评价中，为此目的调查了婴儿奶中的 BaP 含量。选择的关键词是：苯并（）芘、BaP、婴儿配方奶粉、奶粉、婴儿食品。在科学数据库中总共找到了 46 篇论文。经过初步筛选和质量评估，选择了 12 篇文章来提取数据。通过荟萃分析，计算出婴儿食品中 BaP 的总估计值为 0.078±0.006μg/kg。还为三个年龄组（0-6 个月、6-12 个月和 1-3 岁）计算了非致癌风险的每日摄入量（EDI）和危害系数（HQ）以及致癌风险的暴露量倍数（MOE）。三个年龄组的 HQ 均低于 1，MOE 均高于 10000。因此，婴儿健康不存在潜在的致癌和非致癌风险。
