[再生与致癌过程中大鼠肾脏的氧疗方案]
[Oxygen regimen of rat kidneys in regeneration and carcinogenesis].
作者信息
Beliaeva N M, Nikolaev V P, Matchin G A
出版信息
Vopr Onkol. 1986;32(4):65-8.
PMID:3705530
Abstract
Oxygen tension in the kidneys in compensatory hyperplasia after nephrectomy and in renal carcinogenesis induced by nitrosodimethylamine was studied in 80 albino noninbred rats. Regeneration and malignant transformation were found to involve similar changes in oxygen conditions in rat's kidneys, viz. disturbances in the function of microvessels and decreased utilization of oxygen.
摘要
在80只白化非近交系大鼠中，研究了肾切除术后代偿性增生以及亚硝基二甲胺诱导的肾癌发生过程中肾脏的氧张力。结果发现，再生和恶性转化过程中大鼠肾脏的氧状况存在相似变化，即微血管功能紊乱和氧利用率降低。
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