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一名72岁患者肾切除标本中的肾嗜酸细胞瘤和肾盂尿路上皮癌

Renal Oncocytoma and Pelvic Urothelial Carcinoma in a Nephrectomy Specimen of a 72-Year-Old Patient.

作者信息

Atique Usman, Atique Muhammad, Nusrat Nadeem B, Muhammad Shujah

机构信息

Histopathology, Pakistan Kidney and Liver Institute and Research Center, Lahore, PAK.

Urology, Pakistan Kidney and Liver Institute and Research Center, Lahore, PAK.

出版信息

Cureus. 2023 Mar 13;15(3):e36061. doi: 10.7759/cureus.36061. eCollection 2023 Mar.

Abstract

We present the case of a 72-year-old gentleman who presented with a left renal mass. His Computerized Tomography Angiogram showed an 11.8 x 11.3 cm mass involving the upper pole of the left kidney. The mass showed a central stellate scar. There was no locoregional lymphadenopathy. His radical nephrectomy specimen was received in our lab. Sectioning showed a large tumor in the upper pole with a central stellate scar. Microscopically, it showed sheets and nests of round cells with eosinophilic cytoplasm and round nuclei. It was positive for CD117 and negative for CK7. The sections from the renal pelvis showed a urothelial carcinoma arising from the urothelial lining and infiltrating the muscular wall of the renal pelvis. This tumor was positive for CK7 and GATA3. In this case report, we present a rare collision tumor of renal oncocytoma and pelvic urothelial carcinoma.

摘要

我们报告一例72岁男性患者,其因左肾肿物前来就诊。他的计算机断层血管造影显示左肾上极有一个11.8×11.3厘米的肿物。该肿物有一个中央星状瘢痕。无局部区域淋巴结肿大。他的根治性肾切除标本被送至我们实验室。切片显示上极有一个大肿瘤,伴有中央星状瘢痕。显微镜下,可见成片及巢状的圆形细胞,胞质嗜酸性,细胞核圆形。CD117呈阳性,CK7呈阴性。肾盂切片显示起源于尿路上皮内衬并浸润肾盂肌壁的尿路上皮癌。该肿瘤CK7和GATA3呈阳性。在本病例报告中,我们呈现了一例罕见的肾嗜酸细胞瘤与肾盂尿路上皮癌的碰撞瘤。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5d88/10091745/9533bff85174/cureus-0015-00000036061-i01.jpg

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本文引用的文献

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Modern Pathologic Diagnosis of Renal Oncocytoma.肾嗜酸细胞瘤的现代病理诊断
J Kidney Cancer VHL. 2017 Oct 9;4(4):1-12. doi: 10.15586/jkcvhl.2017.96. eCollection 2017.

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