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更年期女性的焦虑症及基于正念减压疗法的干预效果

Anxiety disorder in menopausal women and the intervention efficacy of mindfulness-based stress reduction.

作者信息

Huang Suna, Wang Zhonghai, Zheng Danyi, Liu Lizhu

机构信息

Guangdong Medical University Dongguan 523808, Guangdong, China.

Department of Gastroenterology, Dalang Hospital of Dongguan Dongguan 523777, Guangdong, China.

出版信息

Am J Transl Res. 2023 Mar 15;15(3):2016-2024. eCollection 2023.

Abstract

OBJECTIVES

The purpose of this study was to investigate the current situation of anxiety disorder in menopausal women and to analyze the intervention effect of Mindfulness-Based Stress Reduction (MBSR).

METHODS

A total of 489 patients diagnosed with menopausal syndrome from July 2021 to June 2022 were selected as the study object. There were 120 patients with menopausal syndrome complicated with anxiety who were screened out by the Generalized Anxiety Disorder (GAD-7). The patients were divided into an experimental group (62 cases) and a control group (58 cases) according to the random number table method. The experimental group received MBSR intervention, and the control group received routine intervention. The present situation of menopausal women's anxiety disorder was analyzed. The Five Facet Mindfulness Questionaire (FFMQ) score, GAD-7 score, follicle stimulating hormone (FSH), estradiol (E2), and 5-hydroxytryptamine (5-HT) levels of the two groups were compared.

RESULTS

After a statistical analysis, it was found that the incidence of anxiety in patients with menopausal syndrome was 24.54% (120/489). The severity of menopausal syndrome was positively correlated with the degree of anxiety (r = 0.621, <0.001). After the intervention, in comparison with the control group, the FFMQ score was higher and the GAD-7 score was lower in the experimental group. The levels of FSH were decreased, and the levels of E2 and 5-HT were increased in both groups, with more significant alterations in the observation group (all <0.05).

CONCLUSIONS

The incidence of anxiety disorder in menopausal women was high and its severity was related to the severity of menopausal syndrome. MBSR intervention can alleviate anxiety symptoms and improve hormone levels in the patients.

摘要

目的

本研究旨在调查绝经后女性焦虑症的现状,并分析基于正念减压疗法(MBSR)的干预效果。

方法

选取2021年7月至2022年6月期间共489例诊断为绝经综合征的患者作为研究对象。通过广泛性焦虑障碍量表(GAD-7)筛查出120例合并焦虑的绝经综合征患者。根据随机数字表法将患者分为实验组(62例)和对照组(58例)。实验组接受MBSR干预,对照组接受常规干预。分析绝经后女性焦虑症的现状。比较两组的五因素正念问卷(FFMQ)得分、GAD-7得分、促卵泡生成素(FSH)、雌二醇(E2)和5-羟色胺(5-HT)水平。

结果

经统计分析,发现绝经综合征患者焦虑症的发生率为24.54%(120/489)。绝经综合征的严重程度与焦虑程度呈正相关(r = 0.621,P<0.001)。干预后,与对照组相比,实验组的FFMQ得分更高,GAD-7得分更低。两组的FSH水平均降低,E2和5-HT水平均升高,观察组的变化更显著(均P<0.05)。

结论

绝经后女性焦虑症的发生率较高,其严重程度与绝经综合征的严重程度相关。MBSR干预可缓解患者的焦虑症状并改善激素水平。

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