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Mutagenic activity of furfural in Salmonella typhimurium TA100.

作者信息

Zdzienicka M, Tudek B, Zieleńska M, Szymczyk T

出版信息

Mutat Res. 1978 Nov;58(2-3):205-9. doi: 10.1016/0165-1218(78)90010-1.

Abstract

The mutagenic activity of furfural was tested in Salmonella typhimurium strains TA98 and TA100. Furfural produced mutations in the TA100 strain, but not in the TA98 strain. A rat-liver microsomal fraction did not increase the mutagenic activity of furfural in either strain. Mutagenic activity of furfural in the TA100 strain was not increased by benzo[alpha]pyrene in the presence of metabolic activation.

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