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氡气疗法对支气管哮喘患儿支气管功能的影响:沙丁胺醇药物功能试验

THE INFLUENCE OF SPELEOTHERAPY ON BRONCHI PASSAGE IN CHILDREN WITH BRONCHIAL ASTHMA USING A PHARMACO-FUNCTIONAL TEST WITH SALBUTAMOL.

机构信息

STATE HIGHER EDUCATIONAL ESTABLISHMENT «UZHHOROD NATIONAL UNIVERSITY», UZHHOROD, UKRAINE.

出版信息

Wiad Lek. 2023;76(3):586-590. doi: 10.36740/WLek202303120.

Abstract

OBJECTIVE

The aim: To investigate the reaction of the bronchi to inhalation of salbutamol in children with different severity of bronchial asthma under the conditions of speleotherapy.

PATIENTS AND METHODS

Materials and methods: 40 children aged 6-15 years were examined, 20 of them had an intermittent course of the disease, 20 had a mild course, and the children were in the inter-relapse period. Determining the function of external respiration (FER) with a pharmaco-functional test (PFT) with salbutamol was carried out in the dynamics of observation before and after treatment and compared with the indicators of 40 healthy children. Speleotherapy was performed based on the children's department of the Ukrainian Allergological Hospital of the village Solotvino.

RESULTS

Results: A decrease in increased bronchial tone and restoration of bronchial patency at all levels of the bronchi in all patients with an intermittent course of the disease and a partial decrease in bronchial hyperreactivity with the improvement of bronchial patency in children with a mild course of bronchial asthma under the influence of speleotherapy was established.

CONCLUSION

Conclusions: Thus, speleotherapy contributes to a positive reaction of the bronchi to inhalation of salbutamol, which is reflected in the normalization of disturbed bronchial tone and the restoration of bronchial patency at all levels of the bronchi, in all patients with an intermittent course and partially with a mild course of the disease.

摘要

目的

在洞穴疗法的条件下,研究不同严重程度支气管哮喘儿童吸入沙丁胺醇时支气管的反应。

患者和方法

材料和方法:检查了 40 名年龄在 6-15 岁的儿童,其中 20 名患有间歇性疾病,20 名患有轻度疾病,并且儿童处于缓解期。在治疗前后的药物功能测试(PFT)中进行呼吸功能(FER)的测定,并与 40 名健康儿童的指标进行比较。洞穴疗法是基于乌克兰索洛蒂文诺村的过敏科医院的儿童部门进行的。

结果

结果:在所有间歇性疾病患者中,支气管张力增加减少,并且所有支气管水平的支气管通畅性恢复,在轻度疾病支气管哮喘患者中,支气管高反应性部分降低,支气管通畅性改善,在洞穴疗法的影响下。

结论

结论:因此,洞穴疗法有助于支气管对沙丁胺醇吸入的积极反应,这反映在所有间歇性和部分轻度疾病患者的支气管张力紊乱和所有支气管水平的支气管通畅性恢复正常。

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