Davies J A, Walford A J
Acta Anaesthesiol Scand. 1986 Feb;30(2):145-7. doi: 10.1111/j.1399-6576.1986.tb02385.x.
Intravenous regional anaesthesia, confined to the distal lower limb and using bupivacaine 0.25%, was studied in 12 patients undergoing orthopaedic procedures to the feet. The technique was well accepted by both surgeons and patients and was free from serious toxicity. Bupivacaine was demonstrated in the systemic venous circulation in every case prior to surgery, whilst the tourniquet remained deflated. The plasma bupivacaine levels were less than that associated with toxicity, except in one case exhibiting signs of minor toxicity (bupivacaine plasma level 1.99 micrograms/ml-1). Reasons for the leak in spite of a well-conducted technique are discussed.
对12例足部接受骨科手术的患者进行了静脉区域麻醉研究，麻醉范围局限于下肢远端，使用0.25%布比卡因。该技术得到了外科医生和患者的良好认可，且无严重毒性。在手术前，每次使用止血带时，均能在全身静脉循环中检测到布比卡因，而止血带仍处于放气状态。除1例出现轻微毒性体征（布比卡因血浆水平为1.99微克/毫升）外，血浆布比卡因水平均低于与毒性相关的水平。本文讨论了尽管技术操作规范仍出现渗漏的原因。
