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肿瘤内微生物组:从微生态位到单细胞。

The intratumoral microbiota: From microniches to single cells.

机构信息

Fred Hutchinson Cancer Center, Seattle, WA, USA.

出版信息

Cell. 2023 Apr 13;186(8):1532-1534. doi: 10.1016/j.cell.2023.03.012.

DOI:10.1016/j.cell.2023.03.012
PMID:37059062
Abstract

Solid tumors are composed of a complex and dynamic collection of cell types. Here I discuss the important relationships between cancer cells and bacterial members of the intratumoral microbiota that may provide a fitness advantage within the tumor ecological niche.

摘要

实体瘤由复杂且动态的细胞类型组成。在这里,我讨论了癌细胞与肿瘤内微生物群细菌成员之间的重要关系,这些关系可能为肿瘤生态位内的适应性优势提供了条件。

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