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富含破骨细胞的未分化膀胱癌及免疫组织化学的诊断价值。病例报告。

Osteoclast-rich undifferentiated carcinoma of the bladder and the diagnostic usefulness of immunohistochemistry. A case report.

机构信息

Departamento de Anatomía Patológica, Clínica Universidad de Navarra, Av. Pío XII, 36, 31008, Pamplona, Navarra, Spain.

Departamento de Anatomía Patológica, Clínica Universidad de Navarra, Av. Pío XII, 36, 31008, Pamplona, Navarra, Spain.

出版信息

Rev Esp Patol. 2023 Apr-Jun;56(2):132-135. doi: 10.1016/j.patol.2022.01.002. Epub 2022 Apr 25.

DOI:10.1016/j.patol.2022.01.002
PMID:37061241
Abstract

Osteoclast-rich undifferentiated carcinoma (ORUC) of the urinary tract is a rare variant of urothelial carcinoma, first described in 1985 by Kitazawa et al. It has a worse prognosis compared to other histological variants of invasive urothelial carcinoma and its diagnosis may prove challenging due to the variability in its immunohistochemical profile. We present a case of ORUC in which GATA3 immunostaining was a useful diagnostic tool.

摘要

富含破骨细胞的未分化癌（ORUC）是尿路上皮癌的一种罕见变异型，于 1985 年由 Kitazawa 等人首次描述。与其他浸润性尿路上皮癌的组织学变异型相比，它的预后更差，由于其免疫组织化学特征的可变性，其诊断可能具有挑战性。我们报告了一例 GATA3 免疫染色有助于诊断的 ORUC 病例。

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