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药师协作药物治疗管理方案对出院带药方案使用和医院再入院的影响。

Impact of a pharmacist collaborative drug therapy management protocol on utilization of a discharge prescription program and hospital readmissions.

机构信息

University of Rochester Medical Center Specialty Pharmacy, Rochester, NY, USA.

Buffalo General Medical Center, Buffalo, NY, USA.

出版信息

Am J Health Syst Pharm. 2023 Aug 4;80(16):1056-1062. doi: 10.1093/ajhp/zxad079.

Abstract

PURPOSE

To evaluate the impact of a collaborative drug therapy management (CDTM) agreement allowing a pharmacist to automatically prescribe refills of discharge medications to patients' preferred outpatient pharmacy on utilization of a hospital discharge prescription program and hospital readmission rates.

METHODS: This was a single-center, quasi-experimental pre-post intervention study. Patients aged 18 years or older discharged from the cardiology services to home were eligible for inclusion in the study. The CDTM agreement was initiated on July 1, 2019. Patients discharged to home from July 1, 2018, to June 30, 2019, were assigned to the historical control group. The primary outcome was the difference in the proportion of 
patients who used the bedside medication delivery service at hospital discharge between the groups. Secondary outcomes included 30-day hospital readmissions and a descriptive analysis of medications prescribed by a pharmacist through the program. A χ2 test was used to assess the primary outcome, and multivariable logistic regression was used to assess hospital readmissions.

RESULTS: In total, 1,704 and 2,200 patients were discharged in the control and CDTM groups, respectively. The CDTM group had a greater proportion of patients who participated in the discharge prescription program compared to the historical control group (77.8% vs 68.7%; P < 0.0001). There was no difference in 30-day hospital readmission rate between the groups (adjusted odds ratio, 1.01; 95% confidence interval, 0.83-1.23; 
P = 0.94).

CONCLUSION

A CDTM protocol to improve the availability of medication refills at a patient's regular outpatient pharmacy improved utilization of a bedside medication delivery service but did not change 30-day readmission rates.

摘要

目的

评估允许药剂师自动为患者出院带药续方至其首选的门诊药房的合作药物治疗管理(CDTM)协议对出院处方计划的利用率和医院再入院率的影响。

方法

这是一项单中心、准实验前后干预研究。从心内科出院回家的 18 岁及以上患者符合纳入研究的条件。CDTM 协议于 2019 年 7 月 1 日启动。2018 年 7 月 1 日至 2019 年 6 月 30 日出院的患者被分配到历史对照组。主要结局是两组患者在出院时使用床边药物配送服务的比例差异。次要结局包括 30 天内的医院再入院和药剂师通过该计划开出处方的描述性分析。采用卡方检验评估主要结局,采用多变量逻辑回归评估医院再入院率。

结果

共有 1704 例和 2200 例患者分别纳入对照组和 CDTM 组。与历史对照组相比,CDTM 组参与出院处方计划的患者比例更高(77.8% vs 68.7%;P<0.0001)。两组 30 天内的医院再入院率无差异(调整后比值比,1.01;95%置信区间,0.83-1.23;P=0.94)。

结论

改善患者常规门诊药房药物续方可及性的 CDTM 方案提高了床边药物配送服务的利用率,但并未改变 30 天内的再入院率。

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