阿达木单抗相关的化脓性汗腺炎背景下的ALK+间变性大细胞淋巴瘤
ALK+ ALCL in the setting of adalimumab-related hidradenitis suppurativa.
作者信息
Craig Alexander, Wen Kwun Wah
机构信息
Department of Pathology University of California San Francisco USA.
Helen Diller Family Comprehensive Cancer Center University of California San Francisco USA.
出版信息
Clin Case Rep. 2023 Apr 12;11(4):e7156. doi: 10.1002/ccr3.7156. eCollection 2023 Apr.
Abstract
This ALK-positive anaplastic large cell lymphoma (ALCL) case highlights the importance of considering ALCL in the setting of iatrogenic immunosuppression in hidradenitis suppurativa patients. Diagnosis of ALCL can be challenging in situations with very low viability/cellularity, negative CD3 and/or other T-cell markers, and immunosuppression.
摘要
该ALK阳性间变性大细胞淋巴瘤（ALCL）病例凸显了在化脓性汗腺炎患者医源性免疫抑制情况下考虑ALCL的重要性。在活力/细胞数量极低、CD3及其他T细胞标志物阴性以及存在免疫抑制的情况下，ALCL的诊断可能具有挑战性。
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