Ozkan Gulay, Sakarya Fatma Betul, Tas Dilara, Yurt Bayram, Ercisli Sezai, Capanoglu Esra
Department of Food Engineering, Faculty of Chemical and Metallurgical Engineering, Istanbul Technical University, 34469 Maslak, Istanbul, Turkey.
Department of Food Engineering, Faculty of Engineering and Architecture, Bingol University, Bingol 12300, Turkey.
ACS Omega. 2023 Mar 28;8(14):12730-12738. doi: 10.1021/acsomega.2c07881. eCollection 2023 Apr 11.
Phenolic compounds in herbs have high antioxidant activities, and their consumption as functional foods may impact human health positively. The main objective of this study was to investigate the total phenolic (TPC) and total flavonoid (TFC) contents as well as total antioxidant capacities (TAC) of bioactive compounds in various infusions prepared by herbs collected from the Bingöl region of Turkey during gastrointestinal digestion. According to the results, while the highest TPC (5836 ± 373 mg GAE/100 g dw), TFC (2301 ± 158 CE/100 g, dw), and TAC (1347 mg TE/100 g dw) were obtained with Mill. species, exhibited the lowest values (863 ± 24 mg GAE/100 g dw, 242 ± 23 CE/100 g dw, 735 ± 47 mg TE/100 g dw, respectively). Gallic acid and chlorogenic acid were the most common phenolic compounds in the infusions. In detail, the highest gallic acid was found in M. Bieb (27.3 ± 0.9 mg/100 g of dw) and the highest chlorogenic acid was observed in (919.2 ± 35.7 mg/100 g of dw). After gastrointestinal digestion, the highest bioaccessibility values of TPC and TFC were determined as 0.6- and 3-fold of the values observed in undigested , respectively. Besides, Pall. had the highest bioaccessibility of TAC according to the DPPH (6.7-fold increase) and CUPRAC (9.7-fold increase) assays. It can be concluded that the use of these medicinal herbs in human dietary intake due to their high bioactive compounds even after digestion can improve nutritional value and contribute to human health.
草药中的酚类化合物具有很高的抗氧化活性，将其作为功能性食品食用可能会对人体健康产生积极影响。本研究的主要目的是调查在模拟胃肠道消化过程中，用从土耳其宾格尔地区采集的草药制备的各种浸液中生物活性化合物的总酚含量（TPC）、总黄酮含量（TFC）以及总抗氧化能力（TAC）。结果显示，在Mill. 物种浸液中获得了最高的TPC（5836 ± 373毫克没食子酸当量/100克干重）、TFC（2301 ± 158毫克儿茶素当量/100克干重）和TAC（1347毫克 Trolox 当量/100克干重），而 浸液中的这些值最低（分别为863 ± 24毫克没食子酸当量/100克干重、242 ± 23毫克儿茶素当量/100克干重、735 ± 47毫克 Trolox 当量/100克干重）。没食子酸和绿原酸是浸液中最常见的酚类化合物。具体而言，在M. Bieb浸液中发现了最高含量的没食子酸（27.3 ± 0.9毫克/100克干重），在 浸液中观察到了最高含量的绿原酸（919.2 ± 35.7毫克/100克干重）。经过胃肠道消化后，TPC和TFC的最高生物可及性值分别确定为未消化浸液中观察值的0.6倍和3倍。此外，根据DPPH（增加6.7倍）和CUPRAC（增加9.7倍）测定法，Pall.浸液的TAC生物可及性最高。可以得出结论，由于这些药草即使在消化后仍具有高生物活性化合物，因此将其用于人类饮食摄入可以提高营养价值并对人类健康有益。
