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胃微生物群失调与感染。

Gastric microbiota dysbiosis and infection.

作者信息

Zhang Ling, Zhao Ming, Fu Xiangsheng

机构信息

Department of Gastroenterology, Clinical Medical College, The First Affiliated Hospital of Chengdu Medical College, Chengdu, Sichuan, China.

出版信息

Front Microbiol. 2023 Mar 30;14:1153269. doi: 10.3389/fmicb.2023.1153269. eCollection 2023.

DOI:10.3389/fmicb.2023.1153269
PMID:37065152
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10098173/
Abstract

() infection is one of the most common causes of gastric disease. The persistent increase in antibiotic resistance worldwide has made eradication challenging for clinicians. The stomach is unsterile and characterized by a unique niche. Communication among microorganisms in the stomach results in diverse microbial fitness, population dynamics, and functional capacities, which may be positive, negative, or neutral. Here, we review gastric microecology, its imbalance, and gastric diseases. Moreover, we summarize the relationship between and gastric microecology, including non- bacteria, fungi, and viruses and the possibility of facilitating eradication by gastric microecology modulation, including probiotics, prebiotics, postbiotics, synbiotics, and microbiota transplantation.

摘要

()感染是胃病最常见的病因之一。全球抗生素耐药性的持续增加给临床医生根除感染带来了挑战。胃并非无菌环境,具有独特的生态位。胃内微生物之间的相互作用导致了多样的微生物适应性、种群动态和功能能力,这些作用可能是积极的、消极的或中性的。在此,我们综述胃微生态、其失衡状态以及胃部疾病。此外,我们总结了(此处原文缺失相关微生物名称)与胃微生态之间的关系,包括非(此处原文缺失相关微生物名称)细菌、真菌和病毒,以及通过调节胃微生态促进(此处原文缺失相关微生物名称)根除的可能性,包括益生菌、益生元、后生元、合生元和微生物群移植。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eda9/10098173/c68641d3e52d/fmicb-14-1153269-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eda9/10098173/475f15c9cb6f/fmicb-14-1153269-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eda9/10098173/c68641d3e52d/fmicb-14-1153269-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eda9/10098173/475f15c9cb6f/fmicb-14-1153269-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eda9/10098173/c68641d3e52d/fmicb-14-1153269-g002.jpg

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Life (Basel). 2025 Jun 23;15(7):999. doi: 10.3390/life15070999.
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