儿童复发性指纤维瘤病。两例的超微结构和免疫组织化学研究。

Recurrent digital fibromatosis of childhood. An ultrastructural and immunohistochemical study of two cases.

作者信息

Zina A M, Rampini E, Fulcheri E, Bundino S, Occella C, Bussolati G

出版信息

Am J Dermatopathol. 1986 Feb;8(1):22-6. doi: 10.1097/00000372-198602000-00004.

DOI:10.1097/00000372-198602000-00004

Abstract

Two cases of recurrent digital fibromatosis of childhood were studied by electron microscopy and immunohistochemistry, using rabbit anti-actin antisera. The tumor cells were typical myofibroblasts, containing inclusion bodies and bundles of microfilaments. Immunohistochemistry showed the presence of actin in these cells, thus proving the myofibroblastic nature of the tumors. Inclusions were negative or showed a weak annular positivity. A possible explanation of these findings is discussed.

摘要

运用兔抗肌动蛋白抗血清，通过电子显微镜和免疫组织化学方法对两例儿童复发性指（趾）纤维瘤病进行了研究。肿瘤细胞为典型的肌成纤维细胞，含有包涵体和成束的微丝。免疫组织化学显示这些细胞中存在肌动蛋白，从而证实了肿瘤的肌成纤维细胞性质。包涵体呈阴性或显示微弱的环状阳性。对这些发现的一种可能解释进行了讨论。