ten Have-Opbroek A A
Anat Embryol (Berl). 1986;174(1):49-57. doi: 10.1007/BF00318335.
For analysis of the structural composition of the pulmonary acinus in the mouse, fixed lungs of adult mice were examined by scanning and transmission electron microscopy. The murine acinus proved to consist of one or two generations of rather short respiratory bronchioles and about three generations of alveolar ducts opening into alveolar sacs. The epithelial cells lining the respiratory bronchioles (except for a sharply demarcated zone in the initial portion of the first-order branch) have a cuboidal or squamous shape and are very probably of the same type as those lining the alveolar ducts and sacs, i.e., small and great alveolar cells and/or their precursor cells. Therefore, this respiratory bronchiole portion may be considered part of the respiratory unit or pulmonary acinus. The initial zone of the first-order branch is lined by columnar epithelium, i.e., bronchial epithelium (mainly Clara cells), and should be assigned to the bronchial system of the lung.
为分析小鼠肺腺泡的结构组成，通过扫描电子显微镜和透射电子显微镜对成年小鼠的固定肺进行了检查。结果表明，小鼠肺腺泡由一代或两代较短的呼吸性细支气管以及大约三代通向肺泡囊的肺泡管组成。呼吸性细支气管的内衬上皮细胞（除了一级分支起始部分的一个界限分明的区域）呈立方形或扁平状，很可能与肺泡管和肺泡囊的内衬上皮细胞属于同一类型，即小肺泡细胞和大肺泡细胞及/或它们的前体细胞。因此，这个呼吸性细支气管部分可被视为呼吸单位或肺腺泡的一部分。一级分支的起始区域内衬柱状上皮，即支气管上皮（主要是克拉拉细胞），应归属于肺的支气管系统。
