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胎盘输血的母体影响。

Maternal implications of placental transfusion.

机构信息

Department of Gynecology and Obstetrics, Division of Maternal-Fetal Medicine, Johns Hopkins School of Medicine, 600 N. Wolfe Street, Phipps 228, Baltimore, MD 228, USA.

Department of Pediatrics, Division of Neonatology, Baylor University Medical Center, Pediatrix Medical Group, Dallas, TX, USA.

出版信息

Semin Perinatol. 2023 Jun;47(4):151733. doi: 10.1016/j.semperi.2023.151733. Epub 2023 Mar 17.

DOI:10.1016/j.semperi.2023.151733
PMID:37068968
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11795642/
Abstract

Placental transfusion for 30-60 s after delivery is recommended by numerous professional societies and is now a common practice. Numerous studies document neonatal benefit with minimal maternal risk when routine neonatal stabilization and active management of the third stage of labor are undertaken during the period of delayed cord clamping. Maternal outcomes do not show any increased incidence of postpartum hemorrhage, or need for blood product transfusion in the case of vaginal delivery or cesarean section. Fetomaternal hemorrhage is also likely decreased with delayed cord clamping. In the case of fetal anomalies, cord management should be individualized according to each special circumstance, but is unlikely to lead to increased maternal morbidity. While few studies have investigated maternal outcomes with umbilical cord milking, this practice has not been as widely adopted. With careful monitoring of maternal and fetal well-being, a period of placental transfusion following delivery is advised for benefit of the neonate without significant maternal risk.

摘要

胎盘输注建议在分娩后持续 30-60 秒,这一建议得到了众多专业协会的认可,目前已成为一种常见做法。大量研究证明,在延迟脐带夹闭期间,常规进行新生儿稳定处理和积极管理第三产程,可使新生儿获益,而对产妇的风险极小。在阴道分娩或剖宫产的情况下,产妇结局并未显示产后出血发生率增加,或需要输血制品。延迟脐带夹闭也可能减少胎儿-母体出血。在胎儿畸形的情况下,应根据具体情况个体化管理脐带,但不太可能导致产妇发病率增加。虽然少数研究调查了脐带挤奶对产妇结局的影响,但这种做法并未广泛采用。在仔细监测母婴健康的情况下,建议在分娩后进行一段时间的胎盘输注,以利于新生儿,而不会对产妇造成明显风险。

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本文引用的文献

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Maternal bleeding complications and neonatal outcomes following early versus delayed umbilical cord clamping in cesarean deliveries for very low birthweight infants.剖宫产时早期与延迟夹闭脐带对极低出生体重儿产妇出血并发症和新生儿结局的影响。
J Perinatol. 2023 Jan;43(1):39-43. doi: 10.1038/s41372-022-01558-4. Epub 2022 Nov 10.
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The effects of placental transfusion on mothers.胎盘输血对母亲的影响。
J Matern Fetal Neonatal Med. 2022 Dec;35(25):9356-9361. doi: 10.1080/14767058.2022.2032636. Epub 2022 Jan 30.
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The Effect of Different Timings of Delayed Cord Clamping of Term Infants on Maternal and Newborn Outcomes in Normal Vaginal Deliveries.足月儿延迟脐带结扎不同时机对正常阴道分娩母婴结局的影响
Cureus. 2021 Aug 14;13(8):e17169. doi: 10.7759/cureus.17169. eCollection 2021 Aug.
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Umbilical Cord Management at Term and Late Preterm Birth: A Meta-analysis.足月和晚期早产儿的脐带管理:一项荟萃分析。
Pediatrics. 2021 Mar;147(3). doi: 10.1542/peds.2020-015404.
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Umbilical Cord Management for Newborns <34 Weeks' Gestation: A Meta-analysis.孕周小于34周新生儿的脐带处理:一项荟萃分析
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Impact of a delayed cord clamping protocol on maternal and neonatal outcomes in patients undergoing term cesarean section.延迟脐带夹闭方案对行择期足月剖宫产产妇及新生儿结局的影响。
J Matern Fetal Neonatal Med. 2022 Dec;35(23):4607-4611. doi: 10.1080/14767058.2020.1857357. Epub 2020 Dec 7.
10
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