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教科书式肝外科手术结局:系统综述。

Textbook Outcomes in Liver Surgery: a Systematic Review.

机构信息

Department of Surgery, The Ohio State University Wexner Medical Center and James Comprehensive Cancer Center, Columbus, OH, USA.

Department of Surgery, Hospital General Universitario Dr. Balmis, Pintor Baeza, 11, 03010, Alicante, Spain.

出版信息

J Gastrointest Surg. 2023 Jun;27(6):1277-1289. doi: 10.1007/s11605-023-05673-1. Epub 2023 Apr 17.

Abstract

BACKGROUND

Assessment of the quality of care among patients undergoing hepatectomy may be inadequate using traditional "siloed" postoperative surgical outcome metrics. In turn, the combination of several quality metrics into a single composite Textbook Outcome in Liver Surgery (TOLS) may be more representative of "ideal" surgical care.

METHODS

Adhering to PRISMA guidelines, a search for primary articles on post-operative TOLS evaluation after hepatectomy was performed. Studies that did not present hepatectomy outcomes, pediatric or transplantation populations, duplicated series, and editorials were excluded. Studies were evaluated in aggregate for methodological variation, TOLS rates, factors associated with TOLS, hospital variation, and overall findings.

RESULTS

Among 207 identified publications, 32 observational cohort studies were selected for inclusion in the review. There was a total of 90,077 hepatic resections performed from 1993 to 2020 in the analytic cohort. While TOLS definitions varied widely, all studies used an "all-or-none" composite structure combining a median of 5 (range: 4-7) discrete parameters. Observed TOLS rates varied in the different reported populations from 11.2 to 77.0%. TOLS was associated with patient, hospital, and operative factors.

CONCLUSIONS

This systematic review summarizes the contemporary international experience with TOLS to assess surgical performance following hepatobiliary surgery. TOLS is a single composite metric that may be more patient-centered, as well as better suited to quantify "optimal" care and compare performance among centers performing liver surgery.

摘要

背景

使用传统的“孤立”术后手术结果指标评估接受肝切除术的患者的护理质量可能是不充分的。反过来,将几个质量指标组合成一个单一的综合教科书肝外科手术结果(TOLS)可能更能代表“理想”的手术护理。

方法

根据 PRISMA 指南,对肝切除术后 TOLS 评估的主要文章进行了检索。未呈现肝切除术后结果、儿科或移植人群、重复系列和社论的研究被排除在外。对研究进行了综合评估,评估其方法学变异、TOLS 率、与 TOLS 相关的因素、医院变异和总体发现。

结果

在 207 篇已确定的出版物中,选择了 32 项观察性队列研究纳入综述。在分析队列中,共有 90077 例肝切除术在 1993 年至 2020 年间进行。虽然 TOLS 的定义差异很大,但所有研究都使用了一种“全有或全无”的组合结构,结合了中位数为 5(范围:4-7)个离散参数。不同报告人群中的观察 TOLS 率从 11.2%到 77.0%不等。TOLS 与患者、医院和手术因素相关。

结论

本系统评价总结了当代国际上使用 TOLS 评估肝胆外科手术后手术表现的经验。TOLS 是一种单一的综合指标,可能更以患者为中心,并且更适合量化“最佳”护理,并比较进行肝手术的中心之间的绩效。

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