Serbin Philip A, Do Dang-Huy, Hinkle Andrew, Wukich Dane, Huo Michael, Sambandam Senthil
Department of Orthopaedic Surgery, UT Southwestern, Dallas, TX, USA.
Arthroplast Today. 2023 Feb 28;20:101107. doi: 10.1016/j.artd.2023.101107. eCollection 2023 Apr.
There is no consensus on whether unicompartmental arthroplasty (UKA) or high tibial osteotomy (HTO) is superior for unicompartmental arthritis. While there are studies comparing revision and complication rates, none matched a large number of patients undergoing HTO and UKA in the United States and compared these outcomes. We investigated TKA conversion rate and the complications following HTO or UKA.
This retrospective study queried the PearlDiver database of all patients undergoing UKA and HTO using CPT codes between January 2011 and January 2020. We compared propensity-matched populations based on age, gender, Charlson comorbidity index, and Elixhauser comorbidity index to compare odds of complications, TKA conversion, and drug use between UKA and HTO groups. Two-independent sample t-test for unequal variances and test of significance were performed.
We found 32,583 UKA patients and 816 HTO patients. Each matched group had 535 patients. One-year complication showed higher risk of pneumonia, hematoma, infection, and mechanical complications among HTO patients. UKA patients used narcotics on average of 10.3 days compared to 9.1 days among HTO patients ( < .01). UKA conversion rates were 4.1%, 5.4%, 7.7%, and 9.2% at 1-, 2-, 5-, and 10-year intervals, respectively. HTO conversion rates were less than 2% at 1- and 2-year intervals, 3.4% at 5-year, and 4.5% at 10-year intervals. This difference was statistically significant at 5- and 10-year intervals ( < .01).
Using large matched cohorts, HTO may be converted to TKA later than UKA in short- to mid-term follow-up, and HTO patients used opioids for shorter duration.
对于单髁关节置换术(UKA)和高位胫骨截骨术(HTO)哪种治疗单髁关节炎更具优势,目前尚无定论。虽然有研究比较了翻修率和并发症发生率,但在美国,没有一项研究匹配了大量接受HTO和UKA的患者并比较这些结果。我们调查了全膝关节置换术(TKA)转化率以及HTO或UKA后的并发症情况。
这项回顾性研究使用2011年1月至2020年1月期间的现行程序编码(CPT),查询了PearlDiver数据库中所有接受UKA和HTO的患者。我们基于年龄、性别、查尔森合并症指数和埃利克斯豪泽合并症指数对倾向匹配人群进行比较,以比较UKA组和HTO组之间并发症、TKA转换和药物使用的几率。进行了方差不等的两独立样本t检验和显著性检验。
我们发现32583例UKA患者和816例HTO患者。每个匹配组有535例患者。1年并发症显示HTO患者发生肺炎、血肿、感染和机械并发症的风险更高。UKA患者平均使用麻醉药品10.3天,而HTO患者为9.1天(P<0.01)。UKA在1年、2年、5年和10年时的转换率分别为4.1%、5.4%、7.7%和9.2%。HTO在1年和2年时的转换率低于2%,5年时为3.4%,10年时为4.5%。在5年和10年时,这种差异具有统计学意义(P<0.01)。
在短期至中期随访中,使用大型匹配队列研究发现,HTO比UKA更晚转换为TKA,且HTO患者使用阿片类药物的时间更短。