Salvioli G P, Faldella G, Alessandroni R, Lanari M, Benfenati L
Arch Dis Child. 1986 Apr;61(4):346-8. doi: 10.1136/adc.61.4.346.
We investigated the effect of prolonged iron supplementation of low birthweight infants on plasma zinc concentrations. Thirty infants (neonatal weight 820-2000 g) were examined at 6 or 12 months of life to assess their iron state and plasma zinc concentration. All of them were feeding on iron fortified formulas, which supply about 1 mg/kg/day of iron. In addition, 14 of them had been receiving 2 mg/kg/day of medicinal ferrous salts for at least five months. The other 16 were not given medicinal iron supplementation. Whereas iron state significantly differed in the two groups, plasma zinc concentrations were similar. Moreover, no zinc values below 75 micrograms/100 ml were found in any case. The results suggest that long term iron supplementation of low birthweight infants, at the recommended doses, does not influence zinc plasma concentrations unfavourably.
我们研究了对低出生体重婴儿长期补充铁剂对血浆锌浓度的影响。对30名婴儿（出生体重820 - 2000克）在6个月或12个月大时进行检查，以评估他们的铁状态和血浆锌浓度。所有婴儿均以铁强化配方奶喂养，这种配方奶每天提供约1毫克/千克的铁。此外，其中14名婴儿至少五个月来一直接受每天2毫克/千克的药用亚铁盐。另外16名婴儿未接受药用铁补充剂。虽然两组的铁状态有显著差异，但血浆锌浓度相似。此外，在任何情况下均未发现锌值低于75微克/100毫升。结果表明，以推荐剂量对低出生体重婴儿长期补充铁剂不会对血浆锌浓度产生不利影响。
