Jansson L, Holmberg L, Ekman R
Acta Paediatr Scand. 1979 Sep;68(5):705-8. doi: 10.1111/j.1651-2227.1979.tb18442.x.
Serum ferritin concentrations were measured during the first 6 months of life in 28 low birth weight infants (mean birth weight 1820 g range 900-2460; mean gestational age 34 weeks range 29-37) fed a standard formula fortified with ferrous sulphate. Fifteen of the infants received supplementary medicinal iron (ferrous succinate) from 3 weeks of age, and 13 only from 2 months of age. All were given vitamin E from 10 days of age. The serum ferritin values did not differ between the groups at 1-2 days, 8-10 weeks or at 6 months. Furthermore, there were no signs of hyperhaemolysis at 8-10 weeks in the group receiving medicinal iron early. The data indicate that the iron content in the formula is sufficient until 2 months of age, but also that thereis no disadvantage in starting medicinal iron at 3 weeks of age, if the diet is sufficient in vitamin E.
对28名低出生体重婴儿（平均出生体重1820克，范围900 - 2460克；平均胎龄34周，范围29 - 37周）在出生后的前6个月测量血清铁蛋白浓度，这些婴儿喂养的是添加硫酸亚铁的标准配方奶。其中15名婴儿从3周龄开始补充药用铁（琥珀酸亚铁），13名婴儿仅从2月龄开始补充。所有婴儿从10日龄开始补充维生素E。两组婴儿在出生1 - 2天、8 - 10周或6个月时血清铁蛋白值无差异。此外，早期接受药用铁的组在8 - 10周时没有高溶血迹象。数据表明，配方奶中的铁含量在2月龄前是足够的，但如果饮食中维生素E充足，在3周龄开始补充药用铁也没有坏处。
