Gibson R S, DeWolfe M S
Acta Paediatr Scand. 1981 Jul;70(4):497-500. doi: 10.1111/j.1651-2227.1981.tb05729.x.
Serum samples were collected from 99 infants at birth, and when they were 1, 3 and 6 months old. Thirty-seven were preterm infants with a mean birthweight of 1880 g and 26--36 wk gestation; 24 were full term low birthweight with a mean birthweight of 2371 g and 38--42 wk gestation; and 38 were full term normal birthweight infants with a mean birthweight of 3590 g and 38--42 wk gestation. Serum zinc concentrations were determined by instrumental neutron activation procedures. No significant differences in serum zinc levels were apparent between sexes or among the 3 groups. Levels were highest at birth and declined during the first 3 months. Between 3 and 6 months, serum zinc levels remained fairly constant, and were lower than reported levels for North American adults. It is concluded that the decline in serum zinc concentration in all three groups was not significantly correlated with birthweight or gestational age and the low birthweight infants in this study did not show any evidence of zinc deficiency. The general decline in serum zinc levels appeared to be associated with low dietary zinc intakes.
从99名婴儿出生时以及1个月、3个月和6个月大时采集血清样本。其中37名是早产儿，平均出生体重为1880克，妊娠26 - 36周；24名是足月低出生体重儿，平均出生体重为2371克，妊娠38 - 42周；38名是足月正常出生体重儿，平均出生体重为3590克，妊娠38 - 42周。血清锌浓度通过仪器中子活化程序测定。性别之间或三组之间血清锌水平无明显差异。出生时水平最高，在头3个月下降。3至6个月期间，血清锌水平保持相当稳定，且低于北美成年人报告的水平。得出的结论是，三组血清锌浓度的下降与出生体重或胎龄无显著相关性，本研究中的低出生体重儿未显示任何锌缺乏的证据。血清锌水平的普遍下降似乎与膳食锌摄入量低有关。
