Plath Michaela, Sand Matthias, Appel Maximilian, Euteneuer Sara, Praetorius Mark, Baumann Ingo, Zaoui Karim
Hals-, Nasen- und Ohrenklinik, Heidelberg University Hospital Head Clinic Center, Heidelberg, Germany.
GESIS, GESIS - Leibnitz-Institut für Sozialwissenschaften in Mannheim, Mannheim, Germany.
Laryngorhinootologie. 2023 Nov;102(11):856-866. doi: 10.1055/a-2047-3806. Epub 2023 Apr 18.
The MD POSI is a disease-specific questionnaire to determine the health-related quality of life (HRQoL) of patients with Menière's disease (MD).
Validity and reliability of the German translation of the MD POSI.
Prospective data analysis of a patient group with vertigo (n = 162), which was treated in the otorhinolaryngology of a University Hospital from 2005-2019. A clinical selection was made according to the new Bárány classification in a "definite" and "probable" Menière's disease. HRQoL was assessed using the German translation of the MD POSI, the Vertigo Symptom Score (VSS) and the Short Form (SF-36). Reliability was measured by Cronbach's α and test-retesting after 12 months and again 2 weeks later. Content and agreement validity were examined.
Cronbach α values greater than 0.9 indicated good internal consistency. There was no statistically significant difference from baseline to 12 months, except for the subscore "during the attack". There were significant positive correlations between the VSS overall/VER/AA and the overall index of the MD POSI and negative significant correlations with the SF-36 domains physical functioning, physical role functioning, social functioning, emotional role functioning, mental well-being. There were low SRM (standardized response mean) values below 0.5.
The German translation of the MD POSI is a valid and reliable instrument to evaluate the impact of MD on patients' disease-specific quality of life.
MD POSI是一种针对梅尼埃病（MD）患者的特定疾病问卷，用于确定其健康相关生活质量（HRQoL）。
MD POSI德语翻译版的有效性和可靠性。
对2005年至2019年在一所大学医院耳鼻喉科接受治疗的眩晕患者组（n = 162）进行前瞻性数据分析。根据新的巴拉尼分类法，在“明确”和“可能”的梅尼埃病中进行临床筛选。使用MD POSI德语翻译版、眩晕症状评分（VSS）和简短形式（SF-36）评估HRQoL。通过Cronbach's α系数以及12个月后和2周后再次进行重测来测量可靠性。检查内容效度和一致性效度。
Cronbach α值大于0.9表明内部一致性良好。从基线到12个月，除了“发作期间”的子评分外，没有统计学上的显著差异。VSS总体/VER/AA与MD POSI的总体指数之间存在显著正相关，与SF-36领域的身体功能、身体角色功能、社会功能、情感角色功能、心理健康存在显著负相关。标准化反应均值（SRM）值低于0.5。
MD POSI德语翻译版是评估MD对患者特定疾病生活质量影响的有效且可靠的工具。
