Mutlu Başak, Kırkım Günay, Mungan Durankaya Serpil, Gürkan Selhan, Başokçu Tahsin Oğuz, Güneri Enis Alpin
Department of Otorhinolaryngology, Unit of Hearing, Speech and Balance, Dokuz Eylül Univeristy School of Medicine, İzmir, Turkey.
Department of Assessment and Evaluation in Education, Ege University School of Medicine, İzmir, Turkey.
J Int Adv Otol. 2018 Aug;14(2):304-311. doi: 10.5152/iao.2017.4386.
Ménière's Disease (MD) is a chronic, non-life threatening inner ear disease, with attacks of disabling vertigo, progressive hearing loss, and tinnitus as the major symptoms. All three symptoms, separately or in combination, cause great distress and have a considerable impact on the quality of life of the patients. The aims of this study were to develop a disease-specific quality of life survey for patients with MD and to analyze the relationships between the audiovestibular findings and the survey.
Following Ear-Nose-Throat examination and audiovestibular tests, the Dokuz Eylül University Meniere's Disease Disability Scale (DEU-MDDS) and Turkish version of the Dizziness Handicap Inventory (DHI-T) were administered to 93 patients with definite MD. Reliability and validity analyses of the scale were performed.
There were 45 (48.4%) male and 48 (51.6%) female patients and the mean age was 48.9±12.1 years. Cronbach's alpha was 0.92 and intraclass correlation coefficients of the DEU-MMDS were significant (p<0.001). Results of the Goodness of Fit Statistics showed that the expression levels of the items were high and the correlation coefficients of each item with the scale were sufficient. There was a statistically significant correlation between DHI-T scores and MDDS. DEU-MDDS was not related to the vestibular tests, age or gender (p>0.05).
The MDDS is a valid and reliable scale as a disease-specific quality of life questionnaire for patients with MD.
梅尼埃病（MD）是一种慢性、非危及生命的内耳疾病，主要症状为发作性致残性眩晕、进行性听力损失和耳鸣。这三种症状单独或合并出现都会给患者带来极大痛苦，并对其生活质量产生相当大的影响。本研究的目的是为MD患者开发一种特定疾病的生活质量调查问卷，并分析听前庭检查结果与该调查问卷之间的关系。
在进行耳鼻喉检查和听前庭测试后，对93例确诊为MD的患者进行了多库兹艾吕尔大学梅尼埃病残疾量表（DEU-MDDS）和眩晕 handicap 量表土耳其语版（DHI-T）的评估。对该量表进行了信效度分析。
男性患者45例（48.4%），女性患者48例（51.6%），平均年龄为48.9±12.1岁。Cronbach's alpha为0.92，DEU-MMDS的组内相关系数具有显著性（p<0.001）。拟合优度统计结果显示，各项目的表达水平较高，且各项目与量表的相关系数充足。DHI-T评分与MDDS之间存在统计学显著相关性。DEU-MDDS与前庭测试、年龄或性别无关（p>0.05）。
MDDS作为一种针对MD患者的特定疾病生活质量问卷，是一种有效且可靠的量表。
