Murphy M P, Gates G A
Department of Otolaryngology-Head and Neck Surgery, University of Washington Medical Center, Seattle 98195-7923, USA.
Ann Otol Rhinol Laryngol. 1999 Apr;108(4):331-7. doi: 10.1177/000348949910800403.
We describe the development and initial psychometric testing of a new self-report instrument for quantifying the impact of Meniere's disease (MD) on patients' lives: the Meniere's Disease Patient-Oriented Severity Index (MD POSI). Eighty-five volunteers with chronic MD took a self-administered MD POSI. The internal consistency form of reliability was determined by calculating Cronbach's alpha. The relationship between total MD POSI problem severity scores and responses to a global question concerning the degree to which his or her MD had changed the patient's life assessed construct-related validity. The total problem severity score yielded excellent reliability (Cronbach's alpha = .928). No significant age or gender effects were seen. A highly statistically significant association was noted between total problem severity scores and the degree to which the patient's life had been changed by his or her MD (Spearman rank correlation = .526, p < .0001), indicating excellent construct-related validity. The material included in the initial questionnaire provides important information that can be used clinically to quantify the impact of MD on patients' health status. A beta version of the instrument is in the process of validation and determination of its sensitivity to change in health status.
我们描述了一种用于量化梅尼埃病（MD）对患者生活影响的新型自我报告工具——梅尼埃病患者导向严重程度指数（MD POSI）的开发及初步心理测量测试。85名慢性MD志愿者自行填写了MD POSI。通过计算克朗巴哈系数来确定可靠性的内部一致性形式。MD POSI问题严重程度总分与关于其MD改变患者生活程度的整体问题回答之间的关系评估了结构相关效度。问题严重程度总分显示出极佳的可靠性（克朗巴哈系数 = 0.928）。未观察到显著的年龄或性别效应。问题严重程度总分与患者生活因MD改变的程度之间存在高度统计学显著关联（斯皮尔曼等级相关系数 = 0.526，p < 0.0001），表明具有极佳的结构相关效度。初始问卷中的内容提供了重要信息，可在临床上用于量化MD对患者健康状况的影响。该工具的测试版正在进行效度验证及其对健康状况变化敏感性的测定。
