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预测慢性病患者的工作残疾:一项前瞻性队列研究。

Predicting work disability among people with chronic conditions: a prospective cohort study.

机构信息

Clinicum, Faculty of Medicine, University of Helsinki, Tukholmankatu 8B, 00014, Helsinki, Finland.

Finnish Institute of Occupational Health, Helsinki, Finland.

出版信息

Sci Rep. 2023 Apr 18;13(1):6334. doi: 10.1038/s41598-023-33120-3.

Abstract

Few risk prediction scores are available to identify people at increased risk of work disability, particularly for those with an existing morbidity. We examined the predictive performance of disability risk scores for employees with chronic disease. We used prospective data from 88,521 employed participants (mean age 43.1) in the Finnish Public Sector Study including people with chronic disorders: musculoskeletal disorder, depression, migraine, respiratory disease, hypertension, cancer, coronary heart disease, diabetes, comorbid depression and cardiometabolic disease. A total of 105 predictors were assessed at baseline. During a mean follow-up of 8.6 years, 6836 (7.7%) participants were granted a disability pension. C-statistics for the 8-item Finnish Institute of Occupational Health (FIOH) risk score, comprising age, self-rated health, number of sickness absences, socioeconomic position, number of chronic illnesses, sleep problems, BMI, and smoking at baseline, exceeded 0.72 for all disease groups and was 0.80 (95% CI 0.80-0.81) for participants with musculoskeletal disorders, 0.83 (0.82-0.84) for those with migraine, and 0.82 (0.81-0.83) for individuals with respiratory disease. Predictive performance was not significantly improved in models with re-estimated coefficients or a new set of predictors. These findings suggest that the 8-item FIOH work disability risk score may serve as a scalable screening tool in identifying individuals with increased risk for work disability.

摘要

目前可用的风险预测评分很少能够识别出工作残疾风险增加的人群,特别是对于那些已经存在疾病的人群。我们研究了残疾风险评分在患有慢性病的员工中的预测性能。我们使用了来自芬兰公共部门研究的前瞻性数据,该研究包括 88521 名在职参与者(平均年龄 43.1 岁),其中包括患有肌肉骨骼疾病、抑郁、偏头痛、呼吸道疾病、高血压、癌症、冠心病、糖尿病、合并抑郁和心血管代谢疾病的患者。在基线时评估了总共 105 个预测因素。在平均 8.6 年的随访期间,有 6836 名(7.7%)参与者获得了残疾抚恤金。芬兰职业健康研究所(FIOH)风险评分的 8 项芬兰研究所(FIOH)风险评分的 C 统计量超过 0.72,适用于所有疾病组,而对于肌肉骨骼疾病患者为 0.80(95%CI 0.80-0.81),偏头痛患者为 0.83(0.82-0.84),呼吸道疾病患者为 0.82(0.81-0.83)。在重新估计系数或一组新的预测因素的模型中,预测性能并未显著提高。这些发现表明,8 项 FIOH 工作残疾风险评分可作为一种可扩展的筛查工具,用于识别工作残疾风险增加的个体。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5720/10113323/5d70d54df9a1/41598_2023_33120_Fig1_HTML.jpg

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