Sales Filipa, Cruz Ana Raquel S, Maldonado Filipa, Cunha Mariana
Anesthesiology, Hospital Pedro Hispano, Matosinhos, PRT.
Cureus. 2023 Mar 17;15(3):e36297. doi: 10.7759/cureus.36297. eCollection 2023 Mar.
Lewis-Sumner syndrome (LSS) is a rare immune-mediated neuromuscular disorder. It shares some clinical and pathological features with chronic inflammatory demyelinating polyneuropathy (CIDP). We report on the anaesthetic management of a patient with LSS. There are several concerns when anaesthetizing patients with demyelinating neuropathies, the main ones being the post-operative worsening of symptoms and respiratory depression related to muscle relaxants. In our experience, the rocuronium effect was prolonged and an even lower dosage (0.4 mg/kg) was sufficient for intubation and maintenance. Sugammadex allowed total reversion of neuromuscular block and no respiratory complications occurred. In conclusion, the combination of lower dose rocuronium and sugammadex was safely used in a patient with LSS.
刘易斯-萨姆纳综合征(LSS)是一种罕见的免疫介导性神经肌肉疾病。它与慢性炎症性脱髓鞘性多发性神经病(CIDP)有一些临床和病理特征。我们报告一例LSS患者的麻醉管理。麻醉脱髓鞘性神经病患者时有几个问题需要关注,主要问题是术后症状加重以及与肌肉松弛剂相关的呼吸抑制。根据我们的经验,罗库溴铵的作用时间延长,更低剂量(0.4mg/kg)就足以用于插管和维持麻醉。舒更葡糖可使神经肌肉阻滞完全逆转,且未发生呼吸并发症。总之,低剂量罗库溴铵和舒更葡糖联合应用于一名LSS患者是安全的。