Baĭbekov I M, Nurullaev L D, Mirzakhmedov B M, Volynskiĭ M A, Il'iasov M M
Arkh Patol. 1986;48(2):64-70.
The mucosa of the gastric stump, abducting and adducting loops of small intestine in patients with peptic ulcers of gastrointestinal anastomosis has been examined with scanning, transmission electron and light microscopy, morphometry, and the study of secretion at various periods after reconstructive surgery combined with vagotomy. An increase of the number of chief and parietal cells in the gastric stump fundal glands, increase of the thickness of the mucosa due to the deepening of the crypts of the adducting and abducting loops of the small intestine, and alteration of the mucosal microrelief of the gastric stump and small intestine are noted in peptic ulcers of gastrointestinal anastomosis especially near the site of anastomosis. This is accompanied by an increase of mucosal secretory activity. Reconstructive operations combined with vagotomy cause a reduction in chief and parietal cells number, smoothing of the mucosal microrelief and decrease of gastric secretory activity.
采用扫描电镜、透射电镜、光学显微镜、形态计量学方法以及对重建手术联合迷走神经切断术后不同时期的分泌情况进行研究，对胃肠吻合口消化性溃疡患者胃残端黏膜以及小肠的内收和外展肠袢进行了检查。在胃肠吻合口消化性溃疡中，尤其是在吻合口附近，可观察到胃残端胃底腺主细胞和壁细胞数量增加，因小肠内收和外展肠袢隐窝加深导致黏膜厚度增加，以及胃残端和小肠黏膜微形态的改变。这伴随着黏膜分泌活性的增加。重建手术联合迷走神经切断术会导致主细胞和壁细胞数量减少，黏膜微形态变平滑，以及胃分泌活性降低。
