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发热性溃疡性坏死性穆夏-哈伯曼病:儿科病例报告及文献复习。

Febrile Ulceronecrotic Mucha-Habermann Disease: A Case Report and Review of Literature in the Paediatric Population.

机构信息

Department of Dermatology, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou, China.

Department of Dermatology, Yes Skin Care Center, Hangzhou, China.

出版信息

Acta Derm Venereol. 2023 Apr 19;103:adv4806. doi: 10.2340/actadv.v103.4806.

Abstract

Febrile ulceronecrotic Mucha-Habermann disease (FUMHD) is a rare fulminant variant of pityriasis lichenoides et varioliformis acuta (PLEVA) that is characterized by a large ulceronecrotic appearance with high fever and a variety of systemic symptoms. We report here a case of FUMHD in a 17-year-old male Chinese patient who was treated successfully with a combination therapy of methotrexate, methylprednisolone, and intravenous immunoglobulin. In addition, a literature review was conducted to summarize the key characteristics of paediatric FUMHD cases.

摘要

发热性溃疡性坏死性蕈样肉芽肿病(FUMHD)是一种罕见的急性进行性 pityriasis lichenoides et varioliformis acuta(PLEVA)变体,其特征是高热和多种全身症状伴有大的溃疡性坏死外观。我们在此报告一例 17 岁中国男性患者的 FUMHD 病例,该患者成功接受了甲氨蝶呤、甲基强的松龙和静脉注射免疫球蛋白联合治疗。此外,还进行了文献回顾,以总结儿科 FUMHD 病例的关键特征。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4387/10128150/3b8798c0fe8e/ActaDV-103-4806-g001.jpg

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