Department of Dermatology, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Department of Dermatology, Yes Skin Care Center, Hangzhou, China.
Acta Derm Venereol. 2023 Apr 19;103:adv4806. doi: 10.2340/actadv.v103.4806.
Febrile ulceronecrotic Mucha-Habermann disease (FUMHD) is a rare fulminant variant of pityriasis lichenoides et varioliformis acuta (PLEVA) that is characterized by a large ulceronecrotic appearance with high fever and a variety of systemic symptoms. We report here a case of FUMHD in a 17-year-old male Chinese patient who was treated successfully with a combination therapy of methotrexate, methylprednisolone, and intravenous immunoglobulin. In addition, a literature review was conducted to summarize the key characteristics of paediatric FUMHD cases.
发热性溃疡性坏死性蕈样肉芽肿病(FUMHD)是一种罕见的急性进行性 pityriasis lichenoides et varioliformis acuta(PLEVA)变体,其特征是高热和多种全身症状伴有大的溃疡性坏死外观。我们在此报告一例 17 岁中国男性患者的 FUMHD 病例,该患者成功接受了甲氨蝶呤、甲基强的松龙和静脉注射免疫球蛋白联合治疗。此外,还进行了文献回顾,以总结儿科 FUMHD 病例的关键特征。