中国老年人认知衰弱的患病率：系统评价和荟萃分析。
Prevalence of cognitive frailty among older adults in China: a systematic review and meta-analysis.
机构信息
School of Nursing and Rehabilitation, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China.
The First Clinical College, Shandong University, Jinan, Shandong, China.
出版信息
BMJ Open. 2023 Apr 19;13(4):e066630. doi: 10.1136/bmjopen-2022-066630.
OBJECTIVE
This study aimed to investigate the prevalence of cognitive frailty among older adults in China.
DESIGN
Systematic review and meta-analysis.
METHODS
We searched the Cochrane Library, PubMed, Web of Science, Embase, China National Knowledge Infrastructure(CNKI), Wanfang, Chinese Biomedical Literature and Weipu (VIP) databases to collect information on the epidemiology of cognitive frailty among older adults in China. The study period was from the establishment of the database to March 2022. Two researchers independently screened the literature, extracted the data and assessed the risk of bias in the included studies. All statistical analyses were performed using Stata V.15.0.
RESULTS
We screened 522 records, of which 28 met the inclusion criteria. The results of the meta-analysis showed that the prevalence of cognitive frailty among older adults in China was 15%(95%CI (0.13%,0.17%)). The prevalence of cognitive frailty was higher in hospitals and nursing homes than in communities. Moreover, the prevalence of cognitive frailty was higher in women than in men. Furthermore, the prevalence rates of cognitive frailty in North China Hospital, older adults aged≥80 years, and illiterate individuals were 25%, 29%, and 55%, respectively.
CONCLUSIONS
In conclusion, in China, the prevalence of cognitive frailty is higher among older adults, is higher in women than in men, is higher in hospitals and nursing homes than in communities, and is higher in North China than other regions. Moreover, the higher the educational level, the lower the prevalence of cognitive frailty. Multimodal interventions for cognitive frailty, including increased exercise, nutritional support, increased socialisation opportunities and multifactorial strategies, may be effective in preventing cognitive frailty. These findings have important implications for adjusting healthcare and social care systems.
PROSPERO REGISTRATION NUMBER
CRD42023390486.
目的
本研究旨在调查中国老年人认知脆弱的流行情况。
设计
系统评价和荟萃分析。
方法
我们检索了 Cochrane 图书馆、PubMed、Web of Science、Embase、中国国家知识基础设施(CNKI)、万方、中国生物医学文献和维普(VIP)数据库，以收集中国老年人认知脆弱流行病学的信息。研究时间为数据库建立至 2022 年 3 月。两名研究人员独立筛选文献，提取数据，并评估纳入研究的偏倚风险。所有统计分析均使用 Stata V.15.0 进行。
结果
我们筛选了 522 条记录，其中 28 条符合纳入标准。荟萃分析结果表明，中国老年人认知脆弱的患病率为 15%(95%CI(0.13%,0.17%))。医院和养老院的认知脆弱患病率高于社区。此外，女性的认知脆弱患病率高于男性。此外，华北医院、≥80 岁老年人和文盲个体的认知脆弱患病率分别为 25%、29%和 55%。
结论
总之，在中国，老年人的认知脆弱患病率较高，女性高于男性，医院和养老院高于社区，华北地区高于其他地区。此外，教育水平越高，认知脆弱的患病率越低。针对认知脆弱的多模式干预，包括增加锻炼、营养支持、增加社交机会和多因素策略，可能对预防认知脆弱有效。这些发现对调整医疗保健和社会保健系统具有重要意义。
PROSPERO 注册号：CRD42023390486。
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