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日常生活工具性活动对认知衰弱者孤独感与抑郁之间关系的调节作用。

Moderating effect of instrumental activities of daily living on the relationship between loneliness and depression in people with cognitive frailty.

作者信息

Zhao Yafang, Huo Xiaopeng, Du Hongdi, Lai Xiaoxing, Li Zhen, Zhang Zhiyuan, Yang Longfei

机构信息

Department of Ophthalmology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, China.

Key Laboratory of Ocular Fundus Diseases, Chinese Academy of Medical Sciences, Beijing, China.

出版信息

BMC Geriatr. 2025 Feb 21;25(1):121. doi: 10.1186/s12877-025-05700-7.

Abstract

BACKGROUND

The identification of depression and loneliness among people with cognitive frailty (CF) could prevent negative psychological and physical health outcomes. Few studies have focused on physical and mental health together, and little is known about the role of daily activity in the association between depression and loneliness among elderly individuals with CF.

OBJECTIVES

To determine the positive effect of loneliness on depression among community-dwelling older adults with CF as well as the moderating effect of instrumental activities of daily living (IADL) on this association.

DESIGN, SETTING, PARTICIPANTS, AND MEASUREMENTS: This cross-sectional study included 529 adults aged 65 years and older from a community-dwelling population who were screened for CF and was conducted from July 2023 to December 2023. The participants were assessed via validation instruments for the following main variables: Short-form Geriatric Depression Scale, Loneliness Questionnaire, Athens Insomnia Scale, Instrumental Activities of Daily Living (IADL), Social Support Scale, and sociodemographic characteristics. The participants were classified as having reversable CF (RCF) or potentially reversable CF (PRCF).

RESULTS

The IADL, depression, insomnia, and loneliness scores were lower among individuals with RCF than among individuals PRCF. The moderating effect of IADL scores shows that the relationship between loneliness and depression has a steeper and positive slope when lower levels of IADL exist, compared with a straight line when there are higher levels of IADL, for this case, the line is less steep and showed negative association.

CONCLUSIONS

The integrity of physical and social connections has a protective effect on the mental health of elderly people with CF. It is necessary to pay attention to disability and loneliness among elderly individuals. Targeted interventions for improving physical activity and social participation seem to be practical and feasible solutions to alleviate depressive symptoms.

摘要

背景

识别认知功能减退(CF)人群中的抑郁和孤独感可预防负面的心理和身体健康结果。很少有研究同时关注身心健康,对于日常活动在老年CF患者抑郁与孤独感关联中的作用知之甚少。

目的

确定孤独感对社区居住的老年CF成年人抑郁的正向影响,以及日常生活工具性活动(IADL)对这种关联的调节作用。

设计、地点、参与者和测量方法:这项横断面研究纳入了2023年7月至2023年12月期间从社区居住人群中筛选出的529名65岁及以上的成年人,这些人接受了CF筛查。通过以下主要变量的验证工具对参与者进行评估:简版老年抑郁量表、孤独感问卷、雅典失眠量表、日常生活工具性活动(IADL)、社会支持量表和社会人口学特征。参与者被分类为患有可逆性CF(RCF)或潜在可逆性CF(PRCF)。

结果

RCF个体的IADL、抑郁、失眠和孤独感得分低于PRCF个体。IADL得分的调节作用表明,与IADL水平较高时的直线关系相比,当IADL水平较低时,孤独感与抑郁之间的关系具有更陡峭的正斜率,在这种情况下,该直线斜率较小且呈负相关。

结论

身体和社会联系的完整性对老年CF患者的心理健康具有保护作用。有必要关注老年人中的残疾和孤独感。针对性地干预以改善身体活动和社会参与似乎是缓解抑郁症状的切实可行的解决方案。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0cd8/11846412/5497b85afeff/12877_2025_5700_Fig1_HTML.jpg

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