Palaniappan Latha, Wang Yun, Fortmann Stephen P
Stanford Prevention Research Center, Stanford University School of Medicine, Stanford, CA, USA.
Ann Epidemiol. 2004 Aug;14(7):499-506. doi: 10.1016/j.annepidem.2003.12.001.
To investigate ethnic variations in coronary heart disease death in California, the authors examined total and CHD-specific mortality among non-Hispanic white (white), Hispanic, non-Hispanic black (black), Chinese, Japanese, and Asian Indian Americans. Deaths were identified in the California Mortality Database and population information was derived from the 1990 and 2000 censuses.
Age-standardized death rates per 100,000 population were calculated for ages 25 to 84 years from 1990 to 2000. Proportional mortality ratios (PMRs) for each sex and age group were calculated by dividing the proportion of deaths due to CHD in each ethnic group by the proportion of deaths due to CHD in the total population.
Blacks had the highest all-cause age-standardized death rates among men (1614) and women (1014). Blacks had the highest CHD death rates among men (272) and women (190). PMRs for CHD were highest in Asian Indian men (161) and women (144), reflective of the higher percentage of CHD deaths compared with all cause deaths in this group. All sex-ethnic groups showed a decline in all cause and CHD mortality compared with the period between 1985 and 1990, except Asian Indian women, who experienced a 16% increase in all cause mortality and 5% increase in CHD mortality.
There is considerable heterogeneity in CHD mortality among ethnic subgroups, and additional research is needed to guide treatment and prevention efforts. Blacks and Asian Indians in California are identified as particularly high risk populations.
为研究加利福尼亚州冠心病死亡的种族差异,作者调查了非西班牙裔白人(白人)、西班牙裔、非西班牙裔黑人(黑人)、华裔、日裔和亚裔印度裔美国人的全因死亡率及冠心病特异性死亡率。死亡信息来自加利福尼亚州死亡率数据库,人口信息来自1990年和2000年的人口普查。
计算1990年至2000年25至84岁每10万人口的年龄标准化死亡率。通过将各民族冠心病死亡比例除以总人口中冠心病死亡比例,计算各性别和年龄组的比例死亡率(PMR)。
黑人在男性(1614)和女性(1014)中的全因年龄标准化死亡率最高。黑人在男性(272)和女性(190)中的冠心病死亡率最高。亚裔印度裔男性(161)和女性(144)的冠心病PMR最高,这反映出该群体中冠心病死亡占全因死亡的比例较高。与1985年至1990年期间相比,所有性别种族组的全因死亡率和冠心病死亡率均有所下降,但亚裔印度裔女性除外,其全因死亡率上升了16%,冠心病死亡率上升了5%。
不同种族亚组的冠心病死亡率存在很大差异,需要进一步研究以指导治疗和预防工作。加利福尼亚州的黑人和亚裔印度裔被确定为特别高危人群。