Keloth Thara, Srinivas Bheemanathi Hanuman, Ganesh Rajesh Nachiappa, Ramesh Andi Sadayandi
Department of Pathology, Sri Manakula Vinayagar Medical College and Hospital, Puducherry, India.
Department of Pathology, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India.
Indian J Pathol Microbiol. 2023 Apr-Jun;66(2):363-365. doi: 10.4103/ijpm.ijpm_590_21.
Metastasis accounts for the most common tumor of the central nervous system (CNS) in adults. Renal cell carcinoma (RCC) is one of the common carcinoma showing brain metastasis, with a predilection for clear cell variant. Chromophobe RCC (ChRCC) in contrast to clear cell RCC shows far less common distant metastasis. When they metastasize, commonly involve the liver, lungs, and lymph nodes. ChRCC metastasizing to the brain is extremely rare. Isolated brain metastasis from RCCs is also uncommon. We report an unusual case of a 54-year-old woman with ChRCC with isolated metastasis to the brain, 2 years after radical nephrectomy for renal mass.
转移是成人中枢神经系统（CNS）最常见的肿瘤。肾细胞癌（RCC）是常见的发生脑转移的癌症之一，以透明细胞型为主。与透明细胞RCC相比，嫌色性RCC（ChRCC）的远处转移要少见得多。当它们发生转移时，通常累及肝脏、肺和淋巴结。ChRCC转移至脑极为罕见。RCC的孤立性脑转移也不常见。我们报告一例不寻常的病例，一名54岁女性，在因肾肿物行根治性肾切除术后2年，发生ChRCC并孤立性转移至脑。
