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用于骨科手术规划的 3D 超声股骨重建。

Femur reconstruction in 3D ultrasound for orthopedic surgery planning.

机构信息

ImFusion GmbH, Munich, Germany.

Musculoskeletal University Center Munich, Department of Orthopedics and Trauma Surgery, Ludwig-Maximilians-University Munich, Munich, Germany.

出版信息

Int J Comput Assist Radiol Surg. 2023 Jun;18(6):1001-1008. doi: 10.1007/s11548-023-02868-4. Epub 2023 Apr 20.

Abstract

PURPOSE

Derotation varisation osteotomy of the proximal femur in pediatric patients usually relies on 2-dimensional X-ray imaging, as CT and MRI still are disadvantageous when applied in small children either due to a high radiation exposure or the need of anesthesia. This work presents a radiation-free non-invasive tool to 3D-reconstruct the femur surface and measure relevant angles for orthopedic diagnosis and surgery planning from 3D ultrasound scans instead.

METHODS

Multiple tracked ultrasound recordings are segmented, registered and reconstructed to a 3D femur model allowing for manual measurements of caput-collum-diaphyseal (CCD) and femoral anteversion (FA) angles. Novel contributions include the design of a dedicated phantom model to mimic the application ex vivo, an iterative registration scheme to overcome movements of a relative tracker only attached to the skin, and a technique to obtain the angle measurements.

RESULTS

We obtained sub-millimetric surface reconstruction accuracy from 3D ultrasound on a custom 3D-printed phantom model. On a pre-clinical pediatric patient cohort, angular measurement errors were [Formula: see text] and eventually [Formula: see text] for CCD and FA angles, respectively, both within the clinically acceptable range. To obtain these results, multiple refinements of the acquisition protocol were necessary, ultimately reaching success rates of up to 67% for achieving sufficient surface coverage and femur reconstructions that allow for geometric measurements.

CONCLUSION

Given sufficient surface coverage of the femur, clinically acceptable characterization of femoral anatomy is feasible from non-invasive 3D ultrasound. The acquisition protocol requires leg repositioning, which can be overcome using the presented algorithm. In the future, improvements of the image processing pipeline and more extensive surface reconstruction error assessments could enable more personalized orthopedic surgery planning using cutting templates.

摘要

目的

小儿患者股骨近端的旋转畸形矫正术通常依赖于二维 X 射线成像,因为 CT 和 MRI 由于辐射暴露量大或需要麻醉,在幼儿中应用仍存在劣势。本研究提出了一种无辐射的非侵入性工具,可通过三维超声扫描对股骨表面进行三维重建,并测量相关角度,用于骨科诊断和手术规划。

方法

对多个跟踪的超声记录进行分割、配准和重建,以构建 3D 股骨模型,从而实现对 caput-collum-diaphyseal (CCD) 和股骨前倾角 (FA) 角度的手动测量。新方法包括设计专用的仿体模型来模拟体外应用,一种迭代配准方案来克服仅附着在皮肤的相对跟踪器的运动,以及一种获得角度测量的技术。

结果

我们在定制的 3D 打印仿体模型上从三维超声获得了亚毫米级的表面重建精度。在一个临床前小儿患者队列中,角度测量误差分别为 [公式:见文本] 和最终为 [公式:见文本],均在临床可接受范围内。为了获得这些结果,需要对采集方案进行多次改进,最终达到足以实现足够的股骨表面覆盖和重建以进行几何测量的成功率高达 67%。

结论

在股骨有足够的表面覆盖的情况下,从非侵入性的 3D 超声可以实现对股骨解剖结构的临床可接受的特征描述。采集方案需要腿部重新定位,通过所提出的算法可以克服这一问题。在未来,改进图像处理管道和更广泛的表面重建误差评估,可以使用切割模板为更个性化的骨科手术规划提供支持。

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