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初级保健监测策略对 COVID-19 相关住院和死亡的影响:意大利北部一个省的回顾性电子病历研究,MAGMA 研究。

The effects of primary care monitoring strategies on COVID-19 related hospitalisation and mortality: a retrospective electronic medical records review in a northern Italian province, the MAGMA study.

机构信息

Department of Primary Care, Local Health Authority of Modena, Modena, Italy.

Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Modena, Italy.

出版信息

Eur J Gen Pract. 2023 Dec;29(2):2186395. doi: 10.1080/13814788.2023.2186395. Epub 2023 Apr 20.

Abstract

BACKGROUND

Most symptomatic SARS-CoV-2 infections produce mild to moderate symptoms. Although most patients are managed in the outpatient setting, little is known about the effect of general practitioners' (GP) management strategies on the outcomes of COVID-19 outpatients in Italy.

OBJECTIVES

Describe the management of Italian GPs of SARS-CoV-2 infected adult patients and explore whether GP active care and monitoring are associated with reducing hospitalisation and death.

METHODS

Retrospective observational study of SARS-CoV-2 infected adult outpatients managed by GPs in Modena (Italy) from March 2020 to April 2021. Information on management and monitoring strategies, patients' socio-demographic characteristics, comorbidities, and outcomes (hospitalisation and death due to COVID-19) were retrieved through an electronic medical record review and analysed descriptively and through multiple logistic regression.

RESULTS

Out of the 5340 patients from 46 GPs included in the study, 3014 (56%) received remote monitoring, and 840 (16%) had at least one home visit. More than 85% of severe or critical patients were actively monitored (73% daily) and 52% were visited at home. Changes over time in patients' therapeutic management were observed in concordance with the guidelines' release. Active daily remote monitoring and home visits were strongly associated with reduced hospitalisation rate (OR 0.52, 95% CI 0.33-0.80 and OR 0.50, 95% CI 0.33-0.78 respectively).

CONCLUSION

GPs effectively managed an increasing number of outpatients during the first waves of the pandemic. Active monitoring and home visits were associated with reduced hospitalisation in COVID-19 outpatients.

摘要

背景

大多数有症状的 SARS-CoV-2 感染产生轻度至中度症状。虽然大多数患者在门诊接受治疗,但对于意大利全科医生(GP)管理策略对 COVID-19 门诊患者结局的影响知之甚少。

目的

描述意大利全科医生管理 SARS-CoV-2 感染成年患者的情况,并探讨 GP 的主动护理和监测是否与降低住院率和死亡率相关。

方法

这是一项回顾性观察性研究,纳入了 2020 年 3 月至 2021 年 4 月在意大利摩德纳由全科医生管理的 SARS-CoV-2 感染成年门诊患者。通过电子病历回顾获取管理和监测策略、患者社会人口学特征、合并症以及结局(COVID-19 导致的住院和死亡)信息,并进行描述性和多因素逻辑回归分析。

结果

在纳入的 46 名全科医生的 5340 名患者中,3014 名(56%)接受了远程监测,840 名(16%)至少接受了一次家访。超过 85%的重症或危重症患者得到了积极监测(73%每天),52%的患者接受了家访。随着指南的发布,患者治疗管理的变化得到了观察。主动的每日远程监测和家访与降低住院率显著相关(OR 0.52,95%CI 0.33-0.80 和 OR 0.50,95%CI 0.33-0.78)。

结论

全科医生在大流行的第一波期间有效地管理了越来越多的门诊患者。积极的监测和家访与 COVID-19 门诊患者的住院率降低相关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/469a/10249457/f762cb08a192/IGEN_A_2186395_F0001_C.jpg

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