CINTESIS@RISE-Centre for Health Technology and Services Research, Faculty of Medicine, University of Porto, Porto, Portugal.
Department of Medical Sciences, University of Aveiro, Aveiro, Portugal.
PLoS One. 2023 Apr 20;18(4):e0284464. doi: 10.1371/journal.pone.0284464. eCollection 2023.
Older patients are more likely to have medication-related problems, which are associated with changes in pharmacokinetics and pharmacodynamics, multimorbidity, and polypharmacy. Polypharmacy and inappropriate prescribing are well-known risk factors which commonly cause adverse clinical outcomes in older people. Prescribers struggle to identify potentially inappropriate medications and to choose an adequate tapering approach.
METHODS/DESIGN: The goal of the study is to translate and culturally adapt MedStopper®, an original English language web-based decision aid system in deprescribing medication, to the Portuguese population. A translation-back translation method, with validation of the obtained Portuguese version of MedStopper® will be used, followed by a comprehension test.
This is the first research in the Portuguese primary care setting that aims to provide a useful online tool for the appropriate prescription of older patients. The translated version in Portuguese version of the MedStopper® tool will represent an advance that seeks to continue improving the management of medications in the elderly. The adaptation into Portuguese of the educational tool provides clinicians with a screening tool to detect potentially inappropriate prescribing in patients older than 65 that reliable and easier to use.
Retrospectively registered.
老年人更容易出现与药代动力学和药效学变化、多种疾病和多种药物相关的药物相关问题。多种药物和不适当的处方是众所周知的风险因素，这些因素通常会导致老年人出现不良的临床结果。医生难以识别潜在的不适当药物，并选择适当的减量方法。
方法/设计：本研究的目标是将英文版的 MedStopper®，一个用于药物减量的基于网络的决策辅助系统，翻译成葡萄牙语，并在葡萄牙人群中进行文化适应性测试。我们将采用翻译-回译的方法，并对获得的 MedStopper®葡萄牙语版本进行验证，然后进行理解测试。
这是葡萄牙初级保健领域的第一项研究，旨在为老年患者的适当处方提供一个有用的在线工具。MedStopper®工具的葡萄牙语翻译版本将是一个进步，旨在继续改善老年人的药物管理。该教育工具的葡萄牙语适应性为临床医生提供了一种筛选工具，以检测 65 岁以上患者中潜在的不适当处方，该工具可靠且易于使用。
回顾性注册。
