Section of Geriatrics, Department of Medicine, Boston University School of Medicine, 72 East Concord Street, Robinson 2, Boston, MA 02118, USA; Boston Medical Center, One Boston Medical Center Place, Boston, MA 02118, USA.
Med Clin North Am. 2020 Sep;104(5):751-765. doi: 10.1016/j.mcna.2020.06.001.
Polypharmacy, the use of five or more medications, is common in older adults. It can lead to the use of potentially inappropriate medications and severe adverse outcomes. Deprescribing is an essential step of the thoughtful prescribing process and it can decrease the use of potentially inappropriate medications. Studies have demonstrated that deprescribing is feasible in the clinical setting, especially when it incorporates patient preferences, shared decision making, and an interdisciplinary team. Medication-specific algorithms can facilitate deprescribing in the clinical setting.
多药治疗，即使用五种或更多种药物，在老年人中很常见。它可能导致使用潜在不适当的药物和严重的不良后果。撤药是深思熟虑的处方过程中的一个重要步骤，它可以减少潜在不适当的药物的使用。研究表明，在临床环境中撤药是可行的，尤其是当它结合了患者的偏好、共同决策和跨学科团队时。特定于药物的算法可以促进临床环境中的撤药。
