[动物反复静脉注射组织凝血活酶后凝血酶的形成及其被抗凝血酶III灭活的情况]
[Formation of thrombin and its inactivation by antithrombin III following repeated intravenous injections of tissue thromboplastin in animals].
作者信息
Pastorova V E
出版信息
Biull Eksp Biol Med. 1986 May;101(5):527-9.
PMID:3708129
Abstract
A breach in the inactivation of thrombin activity by antithrombin III following numerous repeated intravenous injections of tissue thromboplastin to albino rats was established. Seven injections of tissue thromboplastin to animals (at 30-40 min-interval) caused functional exhaustion of anticoagulation system and increased thrombin blood circulation level.
摘要
通过对白化大鼠多次重复静脉注射组织凝血活酶，发现抗凝血酶III对凝血酶活性的灭活作用出现了破坏。给动物注射七次组织凝血活酶（间隔30 - 40分钟）导致抗凝系统功能衰竭，并使循环血液中的凝血酶水平升高。
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