Abeles Elisabeth B, Umrau Kavita, Gray Mingyang L, Boahene Kofi D
Department of Otolaryngology, Division of Facial Plastic and Reconstructive Surgery, Johns Hopkins Hospital, Baltimore, Maryland, USA.
Department of Pathology, Johns Hopkins Hospital, Baltimore, Maryland, USA.
J Oral Maxillofac Pathol. 2022 Oct-Dec;26(4):572-575. doi: 10.4103/jomfp.jomfp_410_21. Epub 2022 Dec 22.
Primary bone lymphomas account for 3-5% of extranodal non-Hodgkin lymphomas in adults and are typically present in the axial skeleton and weight-bearing bones. We present a unique case of primary bone diffuse large B-cell lymphoma (DLBCL) of the nasal bone and palate. We discuss the pathologic and radiologic findings and review the current literature and clinical management to highlight how this unusual clinical entity should be considered in differential diagnoses of head and neck bone masses.
原发性骨淋巴瘤占成人结外非霍奇金淋巴瘤的3% - 5%,通常发生于中轴骨骼和负重骨。我们报告一例罕见的鼻骨和腭部原发性骨弥漫性大B细胞淋巴瘤(DLBCL)病例。我们讨论其病理和影像学表现,并回顾当前文献及临床处理方法,以强调在头颈部骨肿块的鉴别诊断中应如何考虑这一特殊的临床实体。