Petes T D
Proc Natl Acad Sci U S A. 1979 Jan;76(1):410-4. doi: 10.1073/pnas.76.1.410.
Two lines of experimental evidence indicate that the repeating ribosomal DNA (rDNA) genes of the yeast Saccharomyces cerevisiae are located on chromosome XII. First, the rDNA genes are linked mitotically to genes that have been previously mapped to chromosome XII. Second, yeast strains that have two copies of the chromosome containing the rDNA genes in every strain examined also have two copies of chromosome XII; this is not true for the other yeast chromosomes. These data also establish that in mitosis most of the rDNA genes in yeast are not extrachromosomal.
两条实验证据表明，酿酒酵母的重复核糖体DNA（rDNA）基因位于第十二号染色体上。首先，rDNA基因在有丝分裂中与先前已定位到第十二号染色体上的基因相连。其次，在所检测的每个菌株中，含有rDNA基因的染色体有两个拷贝的酵母菌株，其第十二号染色体也有两个拷贝；而其他酵母染色体并非如此。这些数据还证实，在有丝分裂过程中，酵母中的大多数rDNA基因并非染色体外基因。
