酿酒酵母核糖体DNA中的不等交换
Unequal crossing over in the ribosomal DNA of Saccharomyces cerevisiae.
作者信息
Szostak J W, Wu R
出版信息
Nature. 1980 Apr 3;284(5755):426-30. doi: 10.1038/284426a0.
DOI:10.1038/284426a0
PMID:6987539
Abstract
Unequal sister chromatid exchanges occur at the ribosomal DNA locus of yeast during mitotic growth. The frequency of unequal crossing over, as measured by the deletion or duplication of an inserted genetic marker (LEU2), is sufficient to maintain the sequence homogeneity of the rDNA repeat units.
摘要
在有丝分裂生长过程中，酵母的核糖体DNA位点会发生不等姐妹染色单体交换。通过插入的遗传标记（LEU2）的缺失或重复来衡量，不等交换的频率足以维持rDNA重复单元的序列同质性。
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