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在埃及,原发性医疗保健门诊就诊的高血压非糖尿病患者中,慢性肾脏病的流行情况如何?

What is the prevalence of chronic kidney disease among hypertensive non-diabetic Egyptian patients attending primary healthcare?

机构信息

Department of Family Medicine, Faculty of Medicine, Ain Shams University, Cairo, Egypt.

Department of Internal Medicine and Nephrology, Faculty of Medicine, Ain Shams University, Cairo, Egypt.

出版信息

Clin Exp Hypertens. 2023 Dec 31;45(1):2203411. doi: 10.1080/10641963.2023.2203411.

DOI:10.1080/10641963.2023.2203411
PMID:37087748
Abstract

BACKGROUND

Although chronic kidney disease (CKD) is considered the major cause of morbidity and mortality in hypertension, the recognition and prevention of CKD remain deficient. CKD is one of the major health challenges in Egypt. CKD affects approximately 13% of the adult population, resulting in significant morbidity, mortality, and health care costs. Patients with more progressive stage 3 or stage 4 CKD experience a high rate of cardiovascular events and death compared to earlier stages of CKD.

AIM

This study was performed to determine the prevalence and risk factors of CKD among hypertensive non-diabetic patients attending primary health care (PHC) centers in Cairo.

METHODOLOGY

The study type is a cross-sectional study. Study setting: Two PHC centers: Saraya El-kobba and El-Sharabya. Sampling method: Recruitment of participants was done in one day weekly. Any known essential hypertensive patients aged 18 or more registered in the two PHC centers in Cairo.

RESULTS

The prevalence of CKD was 33% among the hypertensive non-diabetic patients. Among CKD participants, the prevalence is more common in females (59.7%) than males (40.3%), in those who completed primary education and in the illiterates and low socioeconomic class. Surprisingly, it is more common in patients with positive family history of CKD and patients with ischemic heart disease and the antihypertensive drugs use.

CONCLUSION

CKD has a high prevalence among hypertensive non-diabetic patients, and it has a significant morbidity and mortality among those patients.

摘要

背景

尽管慢性肾脏病(CKD)被认为是高血压患者发病率和死亡率的主要原因,但对 CKD 的认识和预防仍存在不足。CKD 是埃及主要的健康挑战之一。CKD 影响约 13%的成年人口,导致发病率、死亡率和医疗保健费用显著增加。与 CKD 的早期阶段相比,处于更进展阶段 3 或 4 的患者经历更高的心血管事件和死亡风险。

目的

本研究旨在确定在开罗的初级保健 (PHC) 中心就诊的非糖尿病高血压患者中 CKD 的患病率和危险因素。

方法

研究类型为横断面研究。研究地点:两个 PHC 中心:Saraya El-kobba 和 El-Sharabya。抽样方法:每周在一天内招募参与者。任何已知的在开罗的两个 PHC 中心登记的 18 岁及以上的原发性高血压患者。

结果

在非糖尿病高血压患者中,CKD 的患病率为 33%。在 CKD 患者中,女性(59.7%)比男性(40.3%)、完成小学教育的人以及文盲和低社会经济阶层更常见。令人惊讶的是,它在有 CKD 家族史阳性的患者以及有缺血性心脏病和使用抗高血压药物的患者中更为常见。

结论

CKD 在非糖尿病高血压患者中的患病率较高,且在这些患者中具有显著的发病率和死亡率。

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