Park Jongho, Kim Yeaeun
Department of Public Health Administration, Gwangju University, Gwangju, South Korea.
Department of Health Care Management, Catholic University of Pusan, Busan, South Korea.
Iran J Public Health. 2023 Feb;52(2):340-349. doi: 10.18502/ijph.v52i2.11887.
Hypertension, diabetes, and hyperlipidemia are common chronic diseases in South Korea, and medication is a key factor in managing these diseases and preventing disease advancement to multimorbidity. This study aimed to evaluate the effect of chronic disease on medication intake and adherence among Koreans.
This study was conducted utilizing data collected from 5,529 individuals that participated in the Korea Health Panel Survey (KHPS) in 2014-2017. The dependent variables were medication intake and adherence, and independent variables included socioeconomic status and the type of chronic disease. The differences in the medication intake and medication adherence by sociodemographic variables and the type of chronic disease were analyzed by chi-square test. The effect of hypertension, diabetes, and hyperlipidemia on medication intake and adherence was analyzed via multiple logistic regression using SAS statistical software.
The rate of medication intake and adherence were significantly different among patients with hypertension, diabetes, and hyperlipidemia, especially lower in patients with hyperlipidemia compared to those with hypertension and diabetes. In multiple logistic regression analysis, the probability of medication intake increased in female gender, older age, medical aid, medication adherence was higher in married, lower educational level and lower household income. Compared to hyperlipidemia, patients with hypertension and diabetes had more likely to take medication as prescribed.
The importance of considering the type of chronic disease in developing and implementing public health programs aiming for improved medication adherence. Targeting better medication intake and adherence for each chronic disease could be a valuable policy strategy to effectively manage chronic diseases as well as prevent their complications.
高血压、糖尿病和高脂血症是韩国常见的慢性病，药物治疗是管理这些疾病以及预防疾病进展为多种合并症的关键因素。本研究旨在评估慢性病对韩国人药物摄入和依从性的影响。
本研究利用了2014年至2017年参与韩国健康面板调查（KHPS）的5529名个体收集的数据。因变量为药物摄入和依从性，自变量包括社会经济地位和慢性病类型。通过卡方检验分析社会人口统计学变量和慢性病类型在药物摄入和药物依从性方面的差异。使用SAS统计软件通过多元逻辑回归分析高血压、糖尿病和高脂血症对药物摄入和依从性的影响。
高血压、糖尿病和高脂血症患者的药物摄入率和依从率存在显著差异，尤其是高脂血症患者与高血压和糖尿病患者相比更低。在多元逻辑回归分析中，女性、年龄较大、享有医疗救助者药物摄入的可能性增加，已婚、教育程度较低和家庭收入较低者药物依从性较高。与高脂血症相比，高血压和糖尿病患者更有可能按规定服药。
在制定和实施旨在提高药物依从性的公共卫生项目时，考虑慢性病类型具有重要意义。针对每种慢性病提高药物摄入和依从性可能是有效管理慢性病及其预防并发症的一项有价值的政策策略。
