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化学髓核溶解术与开放性椎间盘切除术。一项十年随访研究。

Chemonucleolysis versus open discectomy. A ten-year follow-up study.

作者信息

Weinstein J N, Lehmann T R, Hejna W, McNeill T, Spratt K

出版信息

Clin Orthop Relat Res. 1986 May(206):50-5.

PMID:3708992
Abstract

Retrospectively 156 patients with an average follow-up period of 10.3 years were classified in two groups. Group I, 85 patients, chose chymopapain as their primary treatment. Group II, 71 patients, elected to have a laminectomy with discectomy. Overall, 98% of patients responded to follow-up investigations. Based on several well-accepted pain outcome measures there were no significant differences between the two groups at ten years. Recurrence rates, however, were greater following open discectomy at one- and ten-year follow-up examination. The question of when to return a patient to work yielded interesting results. Those patients returning to work before feeling completely recovered from symptoms had a poorer outcome at final follow-up examination.

摘要

回顾性地将156例平均随访期为10.3年的患者分为两组。第一组85例患者,选择木瓜凝乳蛋白酶作为主要治疗方法。第二组71例患者,选择进行椎板切除术和椎间盘切除术。总体而言,98%的患者接受了随访调查。基于几种广泛认可的疼痛结局指标,两组在十年时没有显著差异。然而,在1年和10年的随访检查中,开放性椎间盘切除术后的复发率更高。关于何时让患者重返工作岗位的问题产生了有趣的结果。那些在症状完全恢复之前就重返工作岗位的患者在最终随访检查中的结局较差。

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