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阿拉伯联合酋长国大学生口服非处方药患者药品信息手册的使用模式:横断面研究

The usage pattern of patients' drug information leaflet for oral non-prescription drugs among university students in the United Arab Emirates: cross-sectional study.

作者信息

Al-Kubaisi Khalid A, Abduelkarem Abduelmula R, Elnour Asim Ahmed, Khidir Israa Yousif El, Hassanein Mohamed M

机构信息

Department of Pharmacy Practice and Pharmacotherapeutics, College of Pharmacy-University of Sharjah, United Arab Emirates.

PhD, MSc. Program of Clinical Pharmacy, College of Pharmacy, Al Ain University, Abu Dhabi campus, Abu Dhabi-United Arab Emirates. AAU Health and Biomedical Research Center, Al Ain University, Abu Dhabi, United Arab Emirates.

出版信息

Pharm Pract (Granada). 2023 Jan-Mar;21(1):2774. doi: 10.18549/PharmPract.2023.1.2774. Epub 2023 Feb 6.

Abstract

BACKGROUND

Very few extensive studies have measured the prevalence and usage pattern of drug information leaflet (DIL) for oral non-prescription drugs (ONPDs) or identified the associated risk factors for not reading DIL among university students in the UAE.

OBJECTIVE

The current study aimed to estimate the prevalence of the usage pattern of DIL for ONPDs, and delineate the associated risk factors for not reading the DIL among university students.

METHODS

A cross-sectional survey-based multistage sampling technique conducted among 2875 students at three major universities in UAE. The self-administered validated questionnaire was constructed and developed based on Andersen's behavioral model. Binomial logistic regression performed to ascertain the effects of 25 potential predictors on the likelihood that participants not reading (discarded) the DIL after reading them. The primary outcome measure was reading (discarding without reading) the DIL, and the associated behaviours.

RESULTS

2875 university students were eligible to participate in the study, but only 2519 students agreed to participate, indicating an 88% of intent participation. However, only 2,355 (81.9%) students completed the questionnaire. 1348 respondents reported using NPD (response rate 46.9%) during the past three months before conducting the study, which comprised the sample analysis (1307 were excluded). More than three-quarters of them read the DIL (always or often) at the first use (1049 of 1348, 77.8%). Approximately a quarter of those who read the DIL reported that they discarded them after reading (24.1%). The survey has identified four risk factors for not reading the DIL: those who get the drug information from physicians or pharmacists had lower odds of discarding the DIL (odds ration [OR] = 0.491, 95% confidence interval [CI]: 0.273-0.884, p value< 0.05). Medical students had lower odds of discarding the DIL (OR = 0.598, 95% CI: 0.412-0.868, p value< 0.05). Those participants who believe that NPDs are as effective as prescription drugs had lower odds of discarding the DIL (OR = 0.342, 95% CI: 0.123-0.948, p value< 0.05). Participants who use more than one NPD to treat a single symptom a day have higher odds of discarding the DIL (OR = 1.625, 95% CI: 1.122 -2.355, p value< 0.05).

CONCLUSION

The prevalence of drug usage pattern in this population was 57.5% as 1348 subjects reported using NPD during the past 90 days before conducting the study. We have identified four risk factors for not reading the DIL, those who get the drug information from physicians or pharmacists, medical students, those respondents who believe that NPDs were as effective as prescription drugs, and respondents self-treating a single symptom with more than one NPD. It was evident from the findings that usage pattern of NPD for DIL varied among the students, with no specific pattern dominating.

摘要

背景

极少有广泛的研究测量过口服非处方药(ONPD)的药品信息单(DIL)的普及率和使用模式,或者确定阿联酋大学生中不阅读DIL的相关风险因素。

目的

本研究旨在估计ONPD的DIL使用模式的普及率,并描述大学生中不阅读DIL的相关风险因素。

方法

在阿联酋三所主要大学的2875名学生中采用基于横断面调查的多阶段抽样技术。基于安德森行为模型构建并开发了自我管理的有效问卷。进行二项逻辑回归以确定25个潜在预测因素对参与者阅读后不阅读(丢弃)DIL可能性的影响。主要结局指标是阅读(不阅读就丢弃)DIL以及相关行为。

结果

2875名大学生有资格参与该研究,但只有2519名学生同意参与,意向参与率为88%。然而,只有2355名(81.9%)学生完成了问卷。1348名受访者报告在开展研究前的过去三个月内使用过非处方药(回复率46.9%),这些构成样本分析对象(排除了1307名)。其中超过四分之三的人在首次使用时(1348人中的1049人,77.8%)阅读了DIL(总是或经常阅读)。大约四分之一阅读了DIL的人报告说他们阅读后就丢弃了DIL(24.1%)。该调查确定了不阅读DIL的四个风险因素:从医生或药剂师处获取药品信息的人丢弃DIL的几率较低(优势比[OR]=0.491,95%置信区间[CI]:0.273 - 0.884,p值<0.05)。医学生丢弃DIL的几率较低(OR = 0.598,95% CI:0.412 - 0.868,p值<0.05)。那些认为非处方药与处方药一样有效的参与者丢弃DIL的几率较低(OR = 0.342,95% CI:0.123 - 0.948,p值<0.05)。每天使用一种以上非处方药治疗单一症状的参与者丢弃DIL的几率较高(OR = 1.625,95% CI:1.122 - 2.355,p值<0.05)。

结论

在开展研究前的过去90天内,有1348名受试者报告使用过非处方药,该人群中药物使用模式的普及率为57.5%。我们确定了不阅读DIL的四个风险因素,即从医生或药剂师处获取药品信息的人、医学生以及那些认为非处方药与处方药一样有效的受访者,还有每天使用一种以上非处方药治疗单一症状的受访者。从研究结果可以明显看出,学生中DIL的非处方药使用模式各不相同,没有一种特定模式占主导。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1df7/10117325/33bdebc158f2/pharmpract-21-2774-g001.jpg

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