Skjørten F, Amlie E, Larsen K A
Eur J Surg Oncol. 1986 Jun;12(2):117-21.
In 1982, a total of 250 breasts were removed for cancer in the surgical departments of the Oslo City Health Department, comprising 81% of all new breast cancers reported in Oslo in 1982. Invasive ductal carcinoma (68%) and invasive lobular carcinoma (12.4%) were the predominant types. Special attention was given to the presence of occult in situ or invasive carcinomas more than 1 cm from the periphery of the main carcinoma. In 24.8% of the specimens, carcinoma in situ was found in such locations, and an additional 6.9% showed a second, occult invasive carcinoma. Carcinoma in situ was equally common in invasive ductal and invasive lobular carcinoma. Occult invasive carcinoma was predominantly found in specimens with invasive lobular carcinoma. There was a significantly increased number of lymph node metastases in patients with carcinoma in situ or second, occult primary carcinoma more than 1 cm from the periphery of the main carcinoma.
1982年，奥斯陆市卫生部门外科共切除250例乳腺癌，占1982年奥斯陆报告的所有新发乳腺癌的81%。浸润性导管癌（68%）和浸润性小叶癌（12.4%）是主要类型。特别关注了距主癌边缘1厘米以上的隐匿性原位癌或浸润性癌的存在情况。在24.8%的标本中，在此类位置发现了原位癌，另有6.9%显示存在第二种隐匿性浸润性癌。原位癌在浸润性导管癌和浸润性小叶癌中同样常见。隐匿性浸润性癌主要见于浸润性小叶癌标本中。距主癌边缘1厘米以上存在原位癌或第二种隐匿性原发性癌的患者，其淋巴结转移数量显著增加。
