Umpleby H C, Herbert A, Royle G T, Taylor I
University Surgical Unit, Southampton General Hospital.
Ann R Coll Surg Engl. 1988 Jul;70(4):246-8.
Fifty-one consecutive women with early breast cancer underwent wide excision and axillary clearance. After wide excision five biopsies were taken from the walls of the cavity. On histological examination tumour was present in the cavity biopsies in 13 cases (25%). The presence of ductal carcinoma in situ in the primary tumour was not associated with an increased number of positive cavity biopsies. In nine cases incomplete excision was due to separate foci of invasive or in situ carcinoma, in two cases tumour was contiguous with the primary carcinoma and in two, separate foci and contiguous disease both occurred. The high incidence of residual local tumour after wide excision of breast cancer demands the need for postoperative irradiation to the breast and frequent review.
51例连续的早期乳腺癌女性患者接受了广泛切除和腋窝清扫术。广泛切除术后，从腔壁取了5块活检组织。组织学检查发现，13例（25%）的腔壁活检组织中有肿瘤。原发肿瘤中导管原位癌的存在与阳性腔壁活检组织数量增加无关。9例切除不完全是由于浸润性或原位癌的独立病灶，2例肿瘤与原发癌相邻，2例同时出现独立病灶和相邻病灶。乳腺癌广泛切除术后局部肿瘤残留的高发生率表明需要进行术后乳房放疗并频繁复查。
