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血液透析机构中的透析专科护理与患者生存率:一项韩国全国队列研究。

Dialysis specialist care and patient survival in hemodialysis facilities: a Korean nationwide cohort study.

作者信息

Park Hayne Cho, Kim Do Hyoung, Cho Ajin, Kwon Young Eun, Ryu Dong-Ryeol, Kim Jinseog, Yang Ki Hwa, Shin Ji Hyeon, Son Eun Jung, Lee Young-Ki

机构信息

Department of Internal Medicine, Hallym University Kangnam Sacred Heart Hospital, Hallym University College of Medicine, Seoul, Republic of Korea.

Hallym University Kidney Research Institute, Seoul, Republic of Korea.

出版信息

Kidney Res Clin Pract. 2023 May;42(3):379-388. doi: 10.23876/j.krcp.22.103. Epub 2023 Mar 22.

Abstract

BACKGROUND

It is important for the dialysis specialist to provide essential and safe care to hemodialysis (HD) patients. However, little is known about the actual effect of dialysis specialist care on the survival of HD patients. We therefore investigated the influence of dialysis specialist care on patient mortality in a nationwide Korean dialysis cohort.

METHODS

We used an HD quality assessment and National Health Insurance Service claims data from October to December 2015. A total of 34,408 patients were divided into two groups according to the proportion of dialysis specialists in their HD unit, as follows: 0%, no dialysis specialist care group, and ≥50%, dialysis specialist care group. We analyzed the mortality risk of these groups using the Cox proportional hazards model after matching propensity scores.

RESULTS

After propensity score matching, 18,344 patients were enrolled. The ratio of patients from the groups with and without dialysis specialist care was 86.7% to 13.3%. The dialysis specialist care group showed a shorter dialysis vintage, higher levels of hemoglobin, higher single-pool Kt/V values, lower levels of phosphorus, and lower systolic and diastolic blood pressures than the no dialysis specialist care group. After adjusting demographic and clinical parameters, the absence of dialysis specialist care was a significant independent risk factor for all-cause mortality (hazard ratio, 1.10; 95% confidence interval, 1.03-1.18; p = 0.004).

CONCLUSION

Dialysis specialist care is an important determinant of overall patient survival among HD patients. Appropriate care given by dialysis specialists may improve clinical outcomes of patients undergoing HD.

摘要

背景

对于透析专科医生而言,为血液透析(HD)患者提供必要且安全的护理至关重要。然而,关于透析专科护理对HD患者生存的实际影响,我们所知甚少。因此,我们在韩国全国性透析队列中调查了透析专科护理对患者死亡率的影响。

方法

我们使用了2015年10月至12月的HD质量评估和国民健康保险服务理赔数据。根据HD单位中透析专科医生的比例,将总共34408名患者分为两组,如下:0%,无透析专科护理组;≥50%,透析专科护理组。在匹配倾向得分后,我们使用Cox比例风险模型分析了这些组的死亡风险。

结果

倾向得分匹配后,纳入了18344名患者。有和没有透析专科护理组的患者比例为86.7%对13.3%。与无透析专科护理组相比,透析专科护理组的透析龄较短、血红蛋白水平较高、单池Kt/V值较高、磷水平较低以及收缩压和舒张压较低。调整人口统计学和临床参数后,无透析专科护理是全因死亡率的显著独立危险因素(风险比,1.10;95%置信区间,1.03 - 1.18;p = 0.004)。

结论

透析专科护理是HD患者总体生存的重要决定因素。透析专科医生提供的适当护理可能会改善HD患者的临床结局。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bbba/10265207/3d0324b0acdf/j-krcp-22-103f1.jpg

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