Torne R, Umbert P
Dermatologica. 1986;172(4):225-8. doi: 10.1159/000249341.
Invasion of the skin by malignant cells in Hodgkin's disease is a rare occurrence and less common than skin involvement in non-Hodgkin's lymphoma. We describe a 36-year-old man with Hodgkin's disease who presented with superficial lymph nodes and tumors on the scalp as initial clinical findings. Biopsy of a tumor of the scalp showed a diffuse dermal infiltrate composed of polynuclear neutrophils and eosinophils, large lymphocytes, and Sternberg-Reed cells. Ultrastructural examination of the skin biopsy specimens demonstrated the characteristic morphology of the Sternberg-Reed cells.
霍奇金病中恶性细胞侵犯皮肤是一种罕见情况，比非霍奇金淋巴瘤的皮肤受累少见。我们描述了一名36岁患有霍奇金病的男性，其最初临床表现为浅表淋巴结肿大和头皮肿物。头皮肿物活检显示真皮弥漫性浸润，由多核中性粒细胞、嗜酸性粒细胞、大淋巴细胞和里-施（Sternberg-Reed）细胞组成。皮肤活检标本的超微结构检查显示了里-施细胞的特征性形态。
