Lityńska A, Wójczyk B
Int J Biochem. 1986;18(6):569-71. doi: 10.1016/0020-711x(86)90170-9.
The rates of protein synthesis and secretion in rat liver slices showed temporal variability, as assessed by the use of [14C]leucine. The protein synthesis showed daily changes with two maxima at 13:00 and 01:00 hr and minimum at 17:00 hr. The secretion rate also varies within 24 hr showing biphasic pattern. The pattern of daily secretion rate for hydrophobic proteins differed from the pattern observed for acid proteins and glycoproteins.
通过使用[14C]亮氨酸评估，大鼠肝切片中的蛋白质合成和分泌速率呈现出时间变异性。蛋白质合成呈现出每日变化，在13:00和01:00时出现两个峰值，在17:00时出现最小值。分泌速率在24小时内也有所变化，呈现出双相模式。疏水蛋白的每日分泌速率模式与酸性蛋白和糖蛋白的模式不同。
