Department of Pediatrics, Xuanwu Hospital Capital Medical University, Beijing, People's Republic of China.
Neuropediatrics. 2023 Dec;54(6):381-387. doi: 10.1055/a-2081-1560. Epub 2023 Apr 26.
Different types of electrical stimulation (ES) showed diverse effects on children with cerebral palsy (CP). Previous studies reported inconsistent results for effects of ES on children with CP. The present study aimed to conduct a meta-analysis to summarize these diverse results.
We searched for studies exploring effects of ES on children with CP in databases (PubMed and Web of Science) from their inception until December 2022. Standard mean differences (SMDs) and 95% confidence intervals (CIs) were computed using STATA 12.0 software.
The meta-analysis included 19 randomized controlled trials (including 265 CP patients in test group and 263 CP patients in corresponding control group). The study showed an increased improvement in gross motor function, walking speed, step length, and daily living activities in ES group compared with corresponding control group with random effects models (gross motor function: SMD = 2.04, 95% CI = 1.43-2.65; walking speed: SMD = 3.71, 95% CI = 1.49-5.92; step length: SMD = 1.89, 95% CI = 0.65-3.13; daily living activities: SMD = 5.18, 95% CI = 3.04-7.31), whereas the study showed no significant difference in change of muscle strength between ES group and the corresponding control group with a random effects model (SMD = 0.42, 95% CI = -0.12 to 0.97).
The study demonstrated that ES might be used as therapy to improve gross motor function, gait, and daily living activities in children with CP.
不同类型的电刺激（ES）对脑瘫（CP）患儿的影响不同。以往的研究报告了 ES 对 CP 患儿的影响结果不一致。本研究旨在进行荟萃分析以总结这些不同的结果。
我们在数据库（PubMed 和 Web of Science）中搜索了从成立到 2022 年 12 月期间探索 ES 对 CP 患儿影响的研究。使用 STATA 12.0 软件计算标准均数差值（SMD）和 95%置信区间（CI）。
荟萃分析纳入了 19 项随机对照试验（试验组包括 265 例 CP 患儿，对照组包括 263 例 CP 患儿）。研究结果显示，与相应的对照组相比，ES 组在粗大运动功能、行走速度、步长和日常生活活动方面的改善更为显著，采用随机效应模型（粗大运动功能：SMD=2.04，95%CI=1.43-2.65；行走速度：SMD=3.71，95%CI=1.49-5.92；步长：SMD=1.89，95%CI=0.65-3.13；日常生活活动：SMD=5.18，95%CI=3.04-7.31），而研究结果显示，ES 组与相应对照组之间肌肉力量的变化无显著差异，采用随机效应模型（SMD=0.42，95%CI=-0.12 至 0.97）。
研究表明，ES 可作为治疗方法，改善 CP 患儿的粗大运动功能、步态和日常生活活动。
